Isobel D Stewart
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Explore the profile of Isobel D Stewart including associated specialties, affiliations and a list of published articles.
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37
Citations
2477
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Recent Articles
1.
Alwan H, Luan J, Williamson A, Carrasco-Zanini J, Stewart I, Wareham N, et al.
EBioMedicine
. 2024 Aug;
107:105306.
PMID: 39191175
Background: Variation in thyroid function parameters within the normal range has been observationally associated with adverse health outcomes. Whether those associations reflect causal effects is largely unknown. Methods: We systematically...
2.
Trichia E, Koulman A, Stewart I, Brage S, Griffin S, Griffin J, et al.
Mol Nutr Food Res
. 2023 Dec;
68(1):e2300154.
PMID: 38054622
Scope: To identify metabolites associated with habitual dairy consumption and investigate their associations with type 2 diabetes (T2D) risk. Methods And Results: Metabolomics assays were conducted in the Fenland (n...
3.
van der Spek A, Stewart I, Kuhnel B, Pietzner M, Alshehri T, Gauss F, et al.
Mol Psychiatry
. 2023 Jul;
28(9):3874-3887.
PMID: 37495887
Metabolome reflects the interplay of genome and exposome at molecular level and thus can provide deep insights into the pathogenesis of a complex disease like major depression. To identify metabolites...
4.
Zhao J, Stewart I, Baird D, Mason D, Wright J, Zheng J, et al.
EBioMedicine
. 2023 Jan;
88:104441.
PMID: 36696816
Background: Amino acids are key to protein synthesis, energy metabolism, cell signaling and gene expression; however, the contribution of specific maternal amino acids to fetal growth is unclear. Methods: We...
5.
Chen Y, Lu T, Pettersson-Kymmer U, Stewart I, Butler-Laporte G, Nakanishi T, et al.
Nat Genet
. 2023 Jan;
55(1):44-53.
PMID: 36635386
Metabolic processes can influence disease risk and provide therapeutic targets. By conducting genome-wide association studies of 1,091 blood metabolites and 309 metabolite ratios, we identified associations with 690 metabolites at...
6.
Surendran P, Stewart I, Au Yeung V, Pietzner M, Raffler J, Worheide M, et al.
Nat Med
. 2022 Nov;
28(11):2321-2332.
PMID: 36357675
Garrod's concept of 'chemical individuality' has contributed to comprehension of the molecular origins of human diseases. Untargeted high-throughput metabolomic technologies provide an in-depth snapshot of human metabolism at scale. We...
7.
Taylor K, McBride N, Zhao J, Oddie S, Azad R, Wright J, et al.
J Cardiovasc Dev Dis
. 2022 Aug;
9(8).
PMID: 36005401
Background: It is plausible that maternal pregnancy metabolism influences the risk of offspring congenital heart disease (CHD). We sought to explore this through a systematic approach using different methods and...
8.
Kachroo P, Stewart I, Kelly R, Stav M, Mendez K, Dahlin A, et al.
Nat Med
. 2022 Jul;
28(8):1723.
PMID: 35859205
No abstract available.
9.
Li C, Imamura F, Wedekind R, Stewart I, Pietzner M, Wheeler E, et al.
Am J Clin Nutr
. 2022 Jun;
116(2):511-522.
PMID: 35754192
Background: Self-reported meat consumption is associated with disease risk but objective assessment of different dimensions of this heterogeneous dietary exposure in observational and interventional studies remains challenging. Objectives: We aimed...
10.
Bomba L, Walter K, Guo Q, Surendran P, Kundu K, Nongmaithem S, et al.
Am J Hum Genet
. 2022 May;
109(6):1038-1054.
PMID: 35568032
Metabolite levels measured in the human population are endophenotypes for biological processes. We combined sequencing data for 3,924 (whole-exome sequencing, WES, discovery) and 2,805 (whole-genome sequencing, WGS, replication) donors from...