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Maik Pietzner

Explore the profile of Maik Pietzner including associated specialties, affiliations and a list of published articles. Areas
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Articles 114
Citations 2783
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Recent Articles
1.
Steinfeldt J, Wild B, Buergel T, Pietzner M, Upmeier Zu Belzen J, Vauvelle A, et al.
Nat Commun . 2025 Feb; 16(1):1507. PMID: 39929799
No abstract available.
2.
Rasooly D, Giambartolomei C, Peloso G, Dashti H, Ferolito B, Golden D, et al.
Nat Cardiovasc Res . 2025 Feb; PMID: 39915329
Heart failure (HF) has limited therapeutic options. In this study, we differentiated the pathophysiological underpinnings of the HF subtypes-HF with reduced ejection fraction (HFrEF) and HF with preserved ejection fraction...
3.
Steinfeldt J, Wild B, Buergel T, Pietzner M, Upmeier Zu Belzen J, Vauvelle A, et al.
Nat Commun . 2025 Jan; 16(1):585. PMID: 39794311
The COVID-19 pandemic exposed a global deficiency of systematic, data-driven guidance to identify high-risk individuals. Here, we illustrate the utility of routinely recorded medical history to predict the risk for...
4.
Jacobs B, Stow D, Hodgson S, Zollner J, Samuel M, Kanoni S, et al.
Nat Commun . 2024 Oct; 15(1):8929. PMID: 39414775
Understanding the genetic basis of routinely-acquired blood tests can provide insights into several aspects of human physiology. We report a genome-wide association study of 42 quantitative blood test traits defined...
5.
Carrasco-Zanini J, Wheeler E, Uluvar B, Kerrison N, Koprulu M, Wareham N, et al.
Nat Metab . 2024 Sep; 6(10):2010-2023. PMID: 39327534
Broad-capture proteomic platforms now enable simultaneous assessment of thousands of plasma proteins, but most of these are not actively secreted and their origins are largely unknown. Here we integrate genomic...
6.
Lockhart S, Muso M, Zvetkova I, Lam B, Ferrari A, Schoenmakers E, et al.
Nat Metab . 2024 Sep; 6(10):1922-1938. PMID: 39322746
Liver X receptor-α (LXRα) regulates cellular cholesterol abundance and potently activates hepatic lipogenesis. Here we show that at least 1 in 450 people in the UK Biobank carry functionally impaired...
7.
Alwan H, Luan J, Williamson A, Carrasco-Zanini J, Stewart I, Wareham N, et al.
EBioMedicine . 2024 Aug; 107:105306. PMID: 39191175
Background: Variation in thyroid function parameters within the normal range has been observationally associated with adverse health outcomes. Whether those associations reflect causal effects is largely unknown. Methods: We systematically...
8.
Carrasco-Zanini J, Pietzner M, Davitte J, Surendran P, Croteau-Chonka D, Robins C, et al.
Nat Med . 2024 Jul; 30(9):2489-2498. PMID: 39039249
For many diseases there are delays in diagnosis due to a lack of objective biomarkers for disease onset. Here, in 41,931 individuals from the United Kingdom Biobank Pharma Proteomics Project,...
9.
Pietzner M, Denaxas S, Yasmeen S, Ulmer M, Nakanishi T, Arnold M, et al.
medRxiv . 2024 Jul; PMID: 39006431
Early evidence that patients with (multiple) pre-existing diseases are at highest risk for severe COVID-19 has been instrumental in the pandemic to allocate critical care resources and later vaccination schemes....
10.
Pietzner M, Denaxas S, Yasmeen S, Ulmer M, Nakanishi T, Arnold M, et al.
Commun Med (Lond) . 2024 Jul; 4(1):94. PMID: 38977844
Background: Early evidence that patients with (multiple) pre-existing diseases are at highest risk for severe COVID-19 has been instrumental in the pandemic to allocate critical care resources and later vaccination...