Isobel Claire Gormley
Overview
Explore the profile of Isobel Claire Gormley including associated specialties, affiliations and a list of published articles.
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15
Citations
147
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Recent Articles
1.
Majumdar K, Silva R, Perry A, Watson R, Rau A, Jaffrezic F, et al.
PLoS One
. 2024 Dec;
19(12):e0314014.
PMID: 39661598
Identifying differentially methylated cytosine-guanine dinucleotide (CpG) sites between benign and tumour samples can assist in understanding disease. However, differential analysis of bounded DNA methylation data often requires data transformation, reducing...
2.
OReilly D, Murphy C, Moore C, Ainle F, Gormley I, Morrell C, et al.
Pediatr Res
. 2023 Sep;
95(3):852-856.
PMID: 37758864
Background: Newborns are at high risk of sepsis. At present there is no definitive "rule in" blood test for sepsis at the point of clinical concern. A positive blood culture...
3.
Gupta S, Gormley I, Brennan L
Metabolites
. 2023 Feb;
13(2).
PMID: 36837783
To date, most metabolomics biomarker research has focused on identifying disease biomarkers. However, there is a need for biomarkers of early metabolic dysfunction to identify individuals who would benefit from...
4.
Frizzarin M, Gormley I, Casa A, McParland S
Foods
. 2021 Dec;
10(12).
PMID: 34945635
Including all available data when developing equations to relate midinfrared spectra to a phenotype may be suboptimal for poorly represented spectra. Here, an alternative local changepoint approach was developed to...
5.
Cotroneo C, Gormley I, Shields D, Salter-Townshend M
BMC Bioinformatics
. 2021 Dec;
22(1):593.
PMID: 34906073
Background: In bacteria, genes with related functions-such as those involved in the metabolism of the same compound or in infection processes-are often physically close on the genome and form groups...
6.
Rafter P, Gormley I, Parnell A, Naderi S, Berry D
Front Genet
. 2021 Nov;
12:761503.
PMID: 34795696
The relative contributions of both copy number variants (CNVs) and single nucleotide polymorphisms (SNPs) to the additive genetic variance of carcass traits in cattle is not well understood. A detailed...
7.
Rafter P, Gormley I, Purfield D, Parnell A, Naderi S, Berry D
BMC Genomics
. 2021 Oct;
22(1):757.
PMID: 34688258
Background: The carcass value of cattle is a function of carcass weight and quality. Given the economic importance of carcass merit to producers, it is routinely included in beef breeding...
8.
DAngelo S, Gormley I, McNamara A, Brennan L
BMC Bioinformatics
. 2021 Sep;
22(1):469.
PMID: 34583648
Background: Metabolomic biomarkers offer potential for objective and reliable food intake assessment, and there is growing interest in using biomarkers in place of or with traditional self-reported approaches. Ongoing research...
9.
Rafter P, Gormley I, Parnell A, Kearney J, Berry D
BMC Genomics
. 2020 Mar;
21(1):205.
PMID: 32131735
Background: The trading of individual animal genotype information often involves only the exchange of the called genotypes and not necessarily the additional information required to effectively call structural variants. The...
10.
Staunton P, Miranda-CasoLuengo A, Loftus B, Gormley I
BMC Bioinformatics
. 2019 Sep;
20(1):466.
PMID: 31500560
Background: Although many of the genic features in Mycobacterium abscessus have been fully validated, a comprehensive understanding of the regulatory elements remains lacking. Moreover, there is little understanding of how...