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Isabelle Seguin

Explore the profile of Isabelle Seguin including associated specialties, affiliations and a list of published articles. Areas
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Articles 6
Citations 233
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Recent Articles
1.
Sheehan N, van Heeswijk R, Foster B, Akhtar H, Singhal N, Seguin I, et al.
Molecules . 2012 Jan; 17(1):688-702. PMID: 22241465
β-Carotene supplements are often taken by individuals living with HIV-1. Contradictory results from in vitro studies suggest that β-carotene may inhibit or induce cytochrome P450 enzymes and transporters. The study...
2.
Porte C, Voduc N, Zhang G, Seguin I, Tardiff D, Singhal N, et al.
Clin Pharmacokinet . 2010 Jun; 49(7):449-54. PMID: 20528005
Background And Objective: Trans-resveratrol is a polyphenol, which is found in red wine and has cancer chemo-preventive properties and disease-preventive properties. The pharmacokinetics of trans-resveratrol have been investigated in single-dose...
3.
van Heeswijk R, Bourbeau M, Campbell P, Seguin I, Chauhan B, Foster B, et al.
J Clin Pharmacol . 2006 Jul; 46(7):758-67. PMID: 16809801
This study investigated the effect of single-dose and steady-state lopinavir/ritonavir on the exposure to fexofenadine, as a measure of P-glycoprotein activity. Sixteen volunteers (8 women) received single-dose oral fexofenadine 120...
4.
van Heeswijk R, Cooper C, Foster B, Chauhan B, Shirazi F, Seguin I, et al.
Pharmacotherapy . 2005 Nov; 25(12):1725-8. PMID: 16305291
Study Objectives: To investigate the effect of high-dose vitamin C on cytochrome P450 (CYP) 3A4 activity, and to evaluate possible sex-specific effects on CYP3A4 activity. Design: Single-center longitudinal study. Setting:...
5.
Cooper C, Davis H, Angel J, Morris M, Elfer S, Seguin I, et al.
AIDS . 2005 Sep; 19(14):1473-9. PMID: 16135900
Background: HIV patients are vaccine hyporesponsive. Methods: We evaluated CPG 7909, a synthetic oligodeoxynucleotide containing immunostimulatory CpG motifs, as an adjuvant to Engerix-B. A randomized, double-blind controlled trial was conducted...
6.
van Heeswijk R, Khaliq Y, Gallicano K, Bourbeau M, Seguin I, Phillips E, et al.
Clin Pharmacol Ther . 2004 Dec; 76(6):588-97. PMID: 15592330
Objective: The objective of this study was to explore the pharmacokinetics of nelfinavir and its active metabolite hydroxy-t-butylamidenelfinavir (M8) during pregnancy and post partum. Methods: Eleven human immunodeficiency virus type...