Isabelle Sahut-Barnola
Overview
Explore the profile of Isabelle Sahut-Barnola including associated specialties, affiliations and a list of published articles.
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31
Citations
776
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Recent Articles
1.
Dufour D, Dumontet T, Sahut-Barnola I, Carusi A, Onzon M, Pussard E, et al.
Nat Commun
. 2022 Dec;
13(1):7858.
PMID: 36543805
SUMOylation is a dynamic posttranslational modification, that provides fine-tuning of protein function involved in the cellular response to stress, differentiation, and tissue development. In the adrenal cortex, an emblematic endocrine...
2.
Wilmouth Jr J, Olabe J, Garcia-Garcia D, Lucas C, Guiton R, Roucher-Boulez F, et al.
Sci Adv
. 2022 Oct;
8(41):eadd0422.
PMID: 36240276
Unlike most cancers, adrenocortical carcinomas (ACCs) are more frequent in women than in men, but the underlying mechanisms of this sexual dimorphism remain elusive. Here, we show that inactivation of...
3.
Sahut-Barnola I, Lefrancois-Martinez A, Dufour D, Botto J, Kamilaris C, Faucz F, et al.
J Invest Dermatol
. 2022 May;
142(11):2949-2957.e9.
PMID: 35568059
Carney complex is a rare familial multineoplastic syndrome predisposing to endocrine and nonendocrine tumors due to inactivating mutations of PRKAR1A, leading to perturbations of the cAMP‒protein kinase A signaling pathway....
4.
Amaya J, Viho E, Sips H, Lalai R, Sahut-Barnola I, Dumontet T, et al.
J Neuroendocrinol
. 2022 Apr;
34(4):e13125.
PMID: 35365898
Excess glucocorticoid exposure affects emotional and cognitive brain functions. The extreme form, Cushing's syndrome, is adequately modelled in the AdKO mouse, consequential to adrenocortical hypertrophy and hypercorticosteronemia. We previously reported...
5.
Djari C, Sahut-Barnola I, Septier A, Plotton I, Montanier N, Dufour D, et al.
J Clin Invest
. 2021 Dec;
131(23).
PMID: 34850745
Large-cell calcifying Sertoli cell tumors (LCCSCTs) are among the most frequent lesions occurring in male Carney complex (CNC) patients. Although they constitute a key diagnostic criterion for this rare multiple...
6.
Amaya J, Suidgeest E, Sahut-Barnola I, Dumontet T, Montanier N, Pages G, et al.
Front Neurosci
. 2021 Mar;
15:604103.
PMID: 33642975
Chronic exposure to high circulating levels of glucocorticoids has detrimental effects on health, including metabolic abnormalities, as exemplified in Cushing's syndrome (CS). Magnetic resonance imaging (MRI) studies have found volumetric...
7.
Tabbal H, Septier A, Mathieu M, Drelon C, Rodriguez S, Djari C, et al.
Br J Cancer
. 2019 Aug;
121(5):384-394.
PMID: 31363169
Background: EZH2 is overexpressed and associated with poor prognosis in adrenocortical carcinoma (ACC) and its inhibition reduces growth and aggressiveness of ACC cells in culture. Although EZH2 was identified as...
8.
Dumontet T, Sahut-Barnola I, Dufour D, Lefrancois-Martinez A, Berthon A, Montanier N, et al.
FASEB J
. 2019 Jun;
33(9):10218-10230.
PMID: 31208233
SUMOylation is a highly conserved and dynamic post-translational mechanism primarily affecting nuclear programs for adapting organisms to stressful challenges. Alteration of SUMOylation cycles leads to severe developmental and homeostatic defects...
9.
Mathieu M, Drelon C, Rodriguez S, Tabbal H, Septier A, Damon-Soubeyrand C, et al.
Proc Natl Acad Sci U S A
. 2018 Dec;
115(52):E12265-E12274.
PMID: 30541888
Adrenal cortex steroids are essential for body homeostasis, and adrenal insufficiency is a life-threatening condition. Adrenal endocrine activity is maintained through recruitment of subcapsular progenitor cells that follow a unidirectional...
10.
Dumontet T, Sahut-Barnola I, Septier A, Montanier N, Plotton I, Roucher-Boulez F, et al.
Ann Endocrinol (Paris)
. 2018 Apr;
79(3):95-97.
PMID: 29673697
The adrenocortical gland undergoes structural and functional remodelling in the fetal and postnatal periods. After birth, the fetal zone of the gland undergoes rapid involution in favor of the definitive...