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Isabelle R Miousse

Explore the profile of Isabelle R Miousse including associated specialties, affiliations and a list of published articles. Areas
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Articles 61
Citations 1166
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Recent Articles
1.
Ferdous K, Tesfay M, Cios A, Shelton R, Hartupee C, Urbaniak A, et al.
Biomedicines . 2024 Jul; 12(7). PMID: 39062169
About one-fourth of patients with pancreatic ductal adenocarcinoma (PDAC) are categorized as borderline resectable (BR) or locally advanced (LA). Chemotherapy and radiation therapy have not yielded the anticipated outcomes in...
2.
Garg S, Miousse I
Nutrients . 2024 Apr; 16(7). PMID: 38613029
Methionine dependence is a characteristic of most cancer cells where they are unable to proliferate when the essential amino acid methionine is replaced with its precursor homocysteine in the growing...
3.
Garg T, Garg S, Miousse I, Wise S, Carpenter A, Fatanmi O, et al.
Radiat Res . 2023 Dec; 201(1):55-70. PMID: 38059553
Currently, no radioprotectors have been approved to mitigate hematopoietic injury after exposure to ionizing radiation. Acute ionizing radiation results in damage to both hematopoietic and immune system cells. Pre-exposure prophylactic...
4.
Morehead L, Koss B, Fil D, Heflin B, Garg S, Wallis K, et al.
Mol Immunol . 2023 Oct; 163:188-195. PMID: 37837954
Immune checkpoint inhibitor therapy has drastically improved outcomes in treating cancer, particularly in melanoma. However, half of melanoma patients are resistant to treatment. One mechanism used by tumor cells to...
5.
Garg S, Morehead L, Bird J, Graw S, Gies A, Storey A, et al.
Mol Omics . 2023 Oct; 20(1):37-47. PMID: 37782107
Dietary methionine restriction is associated with a reduction in tumor growth in preclinical studies and an increase in lifespan in animal models. The mechanism by which methionine restriction inhibits tumor...
6.
Morehead L, Garg S, Wallis K, Simoes C, Siegel E, Tackett A, et al.
Cancers (Basel) . 2023 Sep; 15(18). PMID: 37760436
Dietary methionine restriction (MR), defined as a reduction of methionine intake by around 80%, has been shown to reproducibly decrease tumor growth and synergize with cancer therapies. In this study,...
7.
Nemec-Bakk A, Sridharan V, Seawright J, Nelson G, Cao M, Singh P, et al.
Life Sci Space Res (Amst) . 2023 Apr; 37:78-87. PMID: 37087182
Purpose: Astronauts on missions beyond low Earth orbit will be exposed to galactic cosmic radiation, and there is concern about potential adverse cardiovascular effects. Most of the research to identify...
8.
Garg S, Morehead L, Bird J, Graw S, Gies A, Storey A, et al.
bioRxiv . 2023 Apr; PMID: 37066392
Dietary methionine restriction is associated with a reduction in tumor growth in preclinical studies and an increase in lifespan in animal models. The mechanism by which methionine restriction inhibits tumor...
9.
Morehead L, Garg S, Wallis K, Siegel E, Tackett A, Miousse I
bioRxiv . 2023 Apr; PMID: 37066240
Dietary methionine restriction, defined as reduction of methionine intake by around 80%, reproducibly decreases tumor growth and synergizes with cancer therapies. Here, we combined dietary methionine restriction with immune checkpoint...
10.
Garg T, Garg S, Miousse I, Wise S, Carpenter A, Fatanmi O, et al.
Int J Mol Sci . 2022 Dec; 23(24). PMID: 36555814
Radiation exposure causes acute damage to hematopoietic and immune cells. To date, there are no radioprotectors available to mitigate hematopoietic injury after radiation exposure. Gamma-tocotrienol (GT3) has demonstrated promising radioprotective...