Isabelle I Salles-Crawley
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Explore the profile of Isabelle I Salles-Crawley including associated specialties, affiliations and a list of published articles.
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15
Citations
132
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Recent Articles
1.
Mereweather L, Harwood D, Ahnstrom J, van Batenburg-Sherwood J, Salles-Crawley I, Crawley J
Sci Adv
. 2025 Feb;
11(6):eadr5250.
PMID: 39908367
Deep vein thrombosis is a major cause of morbidity and mortality worldwide. However, because of the absence of overt blood vessel damage, how venous thrombosis is actually initiated remains unclear....
2.
Watson B, Watson B, Salles-Crawley I
Blood Adv
. 2024 Oct;
9(2):427-428.
PMID: 39437796
No abstract available.
3.
Petri A, Sasikumar P, Folgado P, Jones D, Xu Y, Ahnstrom J, et al.
Sci Adv
. 2024 Feb;
10(5):eadk5836.
PMID: 38306422
Tissue factor pathway inhibitor α (TFPIα) is the major physiological regulator of the initiation of blood coagulation. In vitro, TFPIα anticoagulant function is enhanced by its cofactor, protein S. To...
4.
Gierula M, Noakes V, Salles-Crawley I, Crawley J, Ahnstrom J
J Thromb Haemost
. 2023 Sep;
21(12):3568-3580.
PMID: 37739040
Background: For maximal TFPIα functionality, 2 synergistic cofactors, protein S and FV-short, are required. Both interact with TFPIα, protein S through Kunitz 3 residues Arg199/Glu226 and FV-short with the C-terminus....
5.
Kahn S, Arnold D, Casari C, Desch K, Devreese K, Favaloro E, et al.
Res Pract Thromb Haemost
. 2023 Aug;
7(4):100193.
PMID: 37538494
This year's Congress of the International Society of Thrombosis and Haemostasis (ISTH) took place in person in Montréal, Canada, from June 24-28, 2023. The conference, held annually, highlighted cutting-edge advances...
6.
Malik A, Sayed A, Han P, Tan M, Watt E, Constantinescu-Bercu A, et al.
Blood
. 2023 Feb;
141(20):2417-2429.
PMID: 36749920
Immune thrombocytopenia (ITP) is traditionally considered an antibody-mediated disease. However, a number of features suggest alternative mechanisms of platelet destruction. In this study, we use a multidimensional approach to explore...
7.
Mereweather L, Constantinescu-Bercu A, Crawley J, Salles-Crawley I
Int J Mol Sci
. 2023 Jan;
24(2).
PMID: 36674781
Platelets are essential for the formation of a haemostatic plug to prevent bleeding, while neutrophils are the guardians of our immune defences against invading pathogens. The interplay between platelets and...
8.
Constantinescu-Bercu A, Wang Y, Woollard K, Mangin P, Vanhoorelbeke K, Crawley J, et al.
Haematologica
. 2021 Jun;
107(4):933-946.
PMID: 34134470
The GPIbT-VWF A1 domain interaction is essential for platelet tethering under high shear. Synergy between GPIbα and GPVI signaling machineries has been suggested previously, however its molecular mechanism remains unclear....
9.
Huang Y, Gu B, Salles-Crawley I, Taylor K, Yu L, Ren J, et al.
Sci Adv
. 2021 Jun;
7(23).
PMID: 34078604
Clinical use of tissue plasminogen activator (tPA) in thrombolytic therapy is limited by its short circulation time and hemorrhagic side effects. Inspired by fibrinogen binding to activated platelets, we report...
10.
Constantinescu-Bercu A, Salles-Crawley I, Crawley J
J Thromb Haemost
. 2020 Jul;
18(7):1556-1558.
PMID: 32619343
No abstract available.