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Isabelle Bardou

Explore the profile of Isabelle Bardou including associated specialties, affiliations and a list of published articles. Areas
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Articles 24
Citations 377
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Recent Articles
1.
Baudron E, Docagne F, Vivien D, Bardou I
Neuroscience . 2024 Nov; 564:236-242. PMID: 39581303
Intestinal immunity is associated with several autoimmune diseases, such as systemic lupus erythematosus, rheumatoid arthritis, and type 1 diabetes. Recent evidence also suggests its implication in the pathogenesis of autoimmune...
2.
Baudron E, Martinez de Lizarrondo S, Gauberti M, Delaunay-Piednoir B, Fournier A, Vivien D, et al.
Brain Behav Immun . 2024 Apr; 119:381-393. PMID: 38604270
Introduction: Multiple sclerosis (MS) is an autoimmune disease of the central nervous system. Recent evidence suggests that lymphocyte trafficking in the intestines could play a key role in its etiology....
3.
Lebas H, Guerit S, Picot A, Boulay A, Fournier A, Vivien D, et al.
Cell Mol Life Sci . 2022 May; 79(6):323. PMID: 35633384
Background: In multiple sclerosis (MS), disturbance of the plasminogen activation system (PAS) and blood brain barrier (BBB) disruption are physiopathological processes that might lead to an abnormal fibrin(ogen) extravasation into...
4.
Hedou E, Douceau S, Chevilley A, Varangot A, Thiebaut A, Triniac H, et al.
Int J Mol Sci . 2021 Dec; 22(24). PMID: 34948279
Tissue-type plasminogen activator (tPA) plays roles in the development and the plasticity of the nervous system. Here, we demonstrate in neurons, that by opposition to the single chain form (sc-tPA),...
5.
Helie P, Camacho-Toledano C, Lesec L, Seillier C, Miralles A, Ortega M, et al.
J Neuroinflammation . 2021 Feb; 18(1):52. PMID: 33610187
Background: Tissue plasminogen activator (tPA) is a serine protease involved in fibrinolysis. It is released by endothelial cells, but also expressed by neurons and glial cells in the central nervous...
6.
Fournier A, Baudron E, Wagnon I, Aubert P, Vivien D, Neunlist M, et al.
Mult Scler J Exp Transl Clin . 2020 Oct; 6(4):2055217320959806. PMID: 33101703
Background: Clinical observations support the hypothesis that stressful events increase relapse occurrence in multiple sclerosis patients, while stress-reduction strategies can modulate this effect. However, a direct cause-effect relationship between stress...
7.
Wagnon I, Helie P, Bardou I, Regnauld C, Lesec L, Leprince J, et al.
Brain . 2020 Sep; 143(10):2957-2972. PMID: 32893288
Anti-N-methyl-d-aspartate receptor (NMDAR) encephalitis is a neuropsychiatric disease characterized by an antibody-mediated autoimmune response against NMDAR. Recent studies have shown that anti-NMDAR antibodies are involved in the pathophysiology of the...
8.
Mehra A, Guerit S, Macrez R, Gosselet F, Sevin E, Lebas H, et al.
J Neurosci . 2020 Jan; 40(8):1778-1787. PMID: 31953371
Increase in blood-brain barrier (BBB) permeability is a crucial step in neuroinflammatory processes. We previously showed that N Methyl D Aspartate Receptor (NMDARs), expressed on cerebral endothelial cells forming the...
9.
Pasquet N, Douceau S, Naveau M, Lesept F, Louessard M, Lebouvier L, et al.
Cereb Cortex . 2018 Jun; 29(6):2482-2498. PMID: 29878094
Modifications of neuronal migration during development, including processes that control cortical lamination are associated with functional deficits at adult stage. Here, we report for the first time that the lack...
10.
Louessard M, Bardou I, Lemarchand E, Thiebaut A, Parcq J, Leprince J, et al.
Cell Death Differ . 2017 Jun; 24(9):1518-1529. PMID: 28644439
The unfolded protein response (UPR) is an endoplasmic reticulum (ER) -related stress conserved pathway that aims to protect cells from being overwhelmed. However, when prolonged, UPR activation converts to a...