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Isabelle Avril

Explore the profile of Isabelle Avril including associated specialties, affiliations and a list of published articles. Areas
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Articles 5
Citations 754
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Recent Articles
1.
Thorel F, Nepote V, Avril I, Kohno K, Desgraz R, Chera S, et al.
Nature . 2010 Apr; 464(7292):1149-54. PMID: 20364121
Pancreatic insulin-producing beta-cells have a long lifespan, such that in healthy conditions they replicate little during a lifetime. Nevertheless, they show increased self-duplication after increased metabolic demand or after injury...
2.
Bonal C, Avril I, Herrera P
Biochem Soc Trans . 2008 May; 36(Pt 3):286-9. PMID: 18481943
The control of glucose metabolism by pancreatic endocrine cells throughout life relies on a tight regulation of the mass of insulin-producing beta-cells. How this homoeostasis is achieved is not well...
3.
Gosmain Y, Avril I, Mamin A, Philippe J
J Biol Chem . 2007 Sep; 282(48):35024-34. PMID: 17901057
Specific expression of the glucagon gene in the rat pancreas requires the presence of the G1 element localized at -100/-49 base pairs on the promoter. Although it is known that...
4.
Ritz-Laser B, Mamin A, Brun T, Avril I, Schwitzgebel V, Philippe J
Mol Endocrinol . 2004 Nov; 19(3):759-70. PMID: 15539431
Gene inactivation studies have shown that members of the Gata family of transcription factors are critical for endoderm development throughout evolution. We show here that Gata-4 and/or Gata-6 are not...
5.
Freemark M, Avril I, Fleenor D, Driscoll P, Petro A, Opara E, et al.
Endocrinology . 2002 Mar; 143(4):1378-85. PMID: 11897695
PRL and placental lactogen (PL) stimulate beta-cell proliferation and insulin gene transcription in isolated islets and rat insulinoma cells, but the roles of the lactogenic hormones in islet development and...