Isabella H Wulur
Overview
Explore the profile of Isabella H Wulur including associated specialties, affiliations and a list of published articles.
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6
Citations
484
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0
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Recent Articles
1.
Bray S, Lee J, Kim S, Hur J, Ebert P, Calley J, et al.
Sci Rep
. 2019 Oct;
9(1):15365.
PMID: 31653970
Anti-EGFR antibodies are effective in therapies for late-stage colorectal cancer (CRC); however, many tumours are unresponsive or develop resistance. We performed genomic analysis of intrinsic and acquired resistance to anti-EGFR...
2.
Konicek B, Capen A, Credille K, Ebert P, Falcon B, Heady G, et al.
Oncotarget
. 2018 Mar;
9(17):13796-13806.
PMID: 29568395
Merestinib is an oral multi-kinase inhibitor targeting a limited number of oncokinases including MET, AXL, RON and MKNK1/2. Here, we report that merestinib inhibits neurotrophic receptor tyrosine kinases NTRK1/2/3 which...
3.
Gong X, Litchfield L, Webster Y, Chio L, Wong S, Stewart T, et al.
Cancer Cell
. 2017 Dec;
32(6):761-776.e6.
PMID: 29232554
Most cancers preserve functional retinoblastoma (Rb) and may, therefore, respond to inhibition of D-cyclin-dependent Rb kinases, CDK4 and CDK6. To date, CDK4/6 inhibitors have shown promising clinical activity in breast...
4.
Kan Z, Zheng H, Liu X, Li S, Barber T, Gong Z, et al.
Genome Res
. 2013 Jun;
23(9):1422-33.
PMID: 23788652
Hepatocellular carcinoma (HCC) is one of the most deadly cancers worldwide and has no effective treatment, yet the molecular basis of hepatocarcinogenesis remains largely unknown. Here we report findings from...
5.
Esseltine J, Willard M, Wulur I, Lajiness M, Barber T, Ferguson S
Mol Pharmacol
. 2013 Jan;
83(4):770-80.
PMID: 23303475
The activity of metabotropic glutamate receptors (mGluRs) is known to be altered as the consequence of neurodegenerative diseases such as Alzheimer, Parkinson, and Huntington disease. However, little attention has been...
6.
Willard M, Lajiness M, Wulur I, Feng B, Swearingen M, Uhlik M, et al.
Mol Cancer Res
. 2012 Apr;
10(6):739-49.
PMID: 22516348
The roles of cholecystokinin 2 receptor (CCK2R) in numerous physiologic processes in the gastrointestinal tract and central nervous system are well documented. There has been some evidence that CCK2R alterations...