Isabel Y Moreno
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Explore the profile of Isabel Y Moreno including associated specialties, affiliations and a list of published articles.
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Articles
11
Citations
60
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Recent Articles
1.
Verma S, Moreno I, Gesteira T, Coulson-Thomas V
Sci Rep
. 2024 Oct;
14(1):24642.
PMID: 39428407
Various techniques using fluorescent reporter probes have been developed, such as GFP transgenic mouse lines that are used to detect spatial-temporal expression levels of genes. Although GFP expression is largely...
2.
Verma S, Moreno I, Prinholato da Silva C, Sun M, Cheng X, Gesteira T, et al.
Ocul Surf
. 2023 Dec;
32:26-38.
PMID: 38151073
Purpose: Tumor necrosis factor (TNF)-stimulated gene-6 (TSG-6) is upregulated in various pathophysiological contexts, where it has a diverse repertoire of immunoregulatory functions. Herein, we investigated the expression and function of...
3.
Verma S, Moreno I, Sun M, Gesteira T, Coulson-Thomas V
Matrix Biol
. 2023 Nov;
124:23-38.
PMID: 37949327
The prevalence of dry eye disease (DED) ranges from ∼5 to 50 % and its associated symptoms decrease productivity and reduce the quality of life. Approximately 85 % of all...
4.
Moreno I, Parsaie A, Gesteira T, Coulson-Thomas V
Invest Ophthalmol Vis Sci
. 2023 Oct;
64(13):48.
PMID: 37906057
Purpose: Limbal epithelial stem cells (LESCs) reside within a LSC niche (LSCN). We recently identified that hyaluronan (HA) is a major constituent of the LSCN, and that HA is necessary...
5.
Lin X, Moreno I, Nguyen L, Gesteira T, Coulson-Thomas V
Biomolecules
. 2023 Sep;
13(9).
PMID: 37759785
A buildup of reactive oxygen species (ROS) occurs in virtually all pathological conditions. Hyaluronan (HA) is a major extracellular matrix component and is susceptible to oxidation by reactive oxygen species...
6.
Verma S, Ogata F, Moreno I, Prinholato da Silva C, Marforio T, Calvaresi M, et al.
Ocul Surf
. 2023 Sep;
30:168-178.
PMID: 37742739
Purpose: Lumican is a major extracellular matrix (ECM) component in the cornea that is upregulated after injury and promotes corneal wound healing. We have recently shown that peptides designed based...
7.
Cappiello F, Verma S, Lin X, Moreno I, Casciaro B, Dutta D, et al.
Biomolecules
. 2023 Jul;
13(7).
PMID: 37509064
The corneal epithelium is a layer in the anterior part of eye that contributes to light refraction onto the retina and to the ocular immune defense. Although an intact corneal...
8.
Verma S, Moreno I, Trapp M, Ramirez L, Gesteira T, Coulson-Thomas V
Differentiation
. 2023 May;
132:41-50.
PMID: 37202278
The Meibomian gland (MG) is an indispensable adnexal structure of eye that produces meibum, an important defensive component for maintaining ocular homeostasis. Normal development and maintenance of the MGs is...
9.
Puri S, Moreno I, Sun M, Verma S, Lin X, Gesteira T, et al.
Stem Cell Res Ther
. 2022 Jul;
13(1):384.
PMID: 35907870
Background: Hyaluronan (HA) has previously been identified as an integral component of the limbal stem cell niche in vivo. In this study, we investigated whether a similar HA matrix is...
10.
Mutoji K, Sun M, Elliott G, Moreno I, Hughes C, Gesteira T, et al.
Int J Mol Sci
. 2021 Jun;
22(11).
PMID: 34071909
Corneal transparency relies on the precise arrangement and orientation of collagen fibrils, made of mostly Type I and V collagen fibrils and proteoglycans (PGs). PGs are essential for correct collagen...