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Isabel Pagani

Explore the profile of Isabel Pagani including associated specialties, affiliations and a list of published articles. Areas
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Articles 25
Citations 588
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Recent Articles
1.
Pagani I, Ghezzi S, Aimola G, Podini P, Genova F, Vicenzi E, et al.
Int J Mol Sci . 2025 Feb; 26(3). PMID: 39940721
Zika virus (ZIKV), a member of the Flaviviridae family, is primarily transmitted through mosquito bites, but can also spread via sexual contact and from mother to fetus. While often asymptomatic,...
2.
Froese J, Mandalari M, Civera M, Elli S, Pagani I, Vicenzi E, et al.
Sci Rep . 2024 Dec; 14(1):32174. PMID: 39741163
The heparan sulfate (HS)-rich extracellular matrix (ECM) serves as an initial interaction site for the homotrimeric spike (S) protein of SARS-CoV-2 to facilitate subsequent docking to angiotensin-converting enzyme 2 (ACE2)...
3.
Pagani I, Venturini A, Capurro V, Nonis A, Ghezzi S, Lena M, et al.
Am J Respir Cell Mol Biol . 2024 Sep; 72(3):308-319. PMID: 39311876
The coronavirus disease (COVID-19) pandemic has underscored the impact of viral infections on individuals with cystic fibrosis (CF). Initial observations suggested lower COVID-19 rates among CF populations; however, subsequent clinical...
4.
Valeri E, Breggion S, Barzaghi F, Abou Alezz M, Crivicich G, Pagani I, et al.
J Exp Med . 2024 Jul; 221(9). PMID: 38953896
Gain-of-function mutations in STING cause STING-associated vasculopathy with onset in infancy (SAVI) characterized by early-onset systemic inflammation, skin vasculopathy, and interstitial lung disease. Here, we report and characterize a novel...
5.
Angioni R, Bonfanti M, Caporale N, Sanchez-Rodriguez R, Munari F, Savino A, et al.
Cell Rep Med . 2023 Nov; 4(11):101266. PMID: 37944530
The spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has fueled the COVID-19 pandemic with its enduring medical and socioeconomic challenges because of subsequent waves and long-term consequences of...
6.
Pagani I, Ottoboni L, Panina-Bordignon P, Martino G, Poli G, Taylor S, et al.
Pharmaceuticals (Basel) . 2023 Oct; 16(10). PMID: 37895856
Zika virus (ZIKV) infection during pregnancy can result in severe birth defects, such as microcephaly, as well as a range of other related health complications. Heparin, a clinical-grade anticoagulant, is...
7.
Unali G, Crivicich G, Pagani I, Abou-Alezz M, Folchini F, Valeri E, et al.
EMBO J . 2023 Mar; 42(10):e112234. PMID: 36970857
The interferon-induced transmembrane proteins (IFITM) are implicated in several biological processes, including antiviral defense, but their modes of action remain debated. Here, taking advantage of pseudotyped viral entry assays and...
8.
Pagani I, Ghezzi S, Alberti S, Poli G, Vicenzi E
Eur Phys J Plus . 2023 Feb; 138(2):157. PMID: 36811098
SARS-CoV-2 is a novel coronavirus that emerged in China at the end of 2019 causing the severe disease known as coronavirus disease 2019 (COVID-19). SARS-CoV-2, as to the previously highly...
9.
Granata V, Pagani I, Morenghi E, Schiavone M, Lezzi A, Ghezzi S, et al.
Int J Mol Sci . 2023 Feb; 24(3). PMID: 36768954
Upon infection, severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) is predicted to interact with diverse cellular functions, such as the nonsense-mediated decay (NMD) pathway, as suggested by the identification of the...
10.
Pagani I, Ottoboni L, Podini P, Ghezzi S, Brambilla E, Bezukladova S, et al.
J Virol . 2022 Sep; 96(19):e0112222. PMID: 36121298
Zika virus (ZIKV) is an arbovirus member of the family that causes severe congenital brain anomalies in infected fetuses. The key target cells of ZIKV infection, human neural progenitor cells...