Isabel M Vincent
Overview
Explore the profile of Isabel M Vincent including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
20
Citations
563
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Steketee P, Giordani F, Vincent I, Crouch K, Achcar F, Dickens N, et al.
PLoS Negl Trop Dis
. 2021 Nov;
15(11):e0009939.
PMID: 34752454
Subspecies of the protozoan parasite Trypanosoma brucei are the causative agents of Human African Trypanosomiasis (HAT), a debilitating neglected tropical disease prevalent across sub-Saharan Africa. HAT case numbers have steadily...
2.
Giordani F, Paape D, Vincent I, Pountain A, Fernandez-Cortes F, Rico E, et al.
PLoS Pathog
. 2020 Nov;
16(11):e1008932.
PMID: 33141865
Livestock diseases caused by Trypanosoma congolense, T. vivax and T. brucei, collectively known as nagana, are responsible for billions of dollars in lost food production annually. There is an urgent...
3.
Lim A, Vincent I, Barrett M, Gilbert I
ACS Omega
. 2019 Nov;
4(21):19199-19215.
PMID: 31763544
The global prevalence of antibacterial resistance requires new antibacterial drugs with novel chemical scaffolds and modes of action. It is also vital to design compounds with optimal physicochemical properties to...
4.
Begolo D, Vincent I, Giordani F, Pohner I, Witty M, Rowan T, et al.
PLoS Pathog
. 2018 Sep;
14(9):e1007315.
PMID: 30252911
Kinetoplastid parasites-trypanosomes and leishmanias-infect millions of humans and cause economically devastating diseases of livestock, and the few existing drugs have serious deficiencies. Benzoxaborole-based compounds are very promising potential novel anti-trypanosomal...
5.
Steketee P, Vincent I, Achcar F, Giordani F, Kim D, Creek D, et al.
PLoS Negl Trop Dis
. 2018 May;
12(5):e0006450.
PMID: 29758036
The parasitic protozoan Trypanosoma brucei causes Human African Trypanosomiasis and Nagana in other mammals. These diseases present a major socio-economic burden to large areas of sub-Saharan Africa. Current therapies involve...
6.
Rattigan K, Pountain A, Regnault C, Achcar F, Vincent I, Goodyear C, et al.
PLoS One
. 2018 Mar;
13(3):e0194126.
PMID: 29538444
Priming and activating immune stimuli have profound effects on macrophages, however, studies generally evaluate stimuli in isolation rather than in combination. In this study we have investigated the effects of...
7.
Zhang N, Zoltner M, Leung K, Scullion P, Hutchinson S, Del Pino R, et al.
PLoS Pathog
. 2018 Feb;
14(2):e1006850.
PMID: 29425238
Recent development of benzoxaborole-based chemistry gave rise to a collection of compounds with great potential in targeting diverse infectious diseases, including human African Trypanosomiasis (HAT), a devastating neglected tropical disease....
8.
Mwenechanya R, Kovarova J, Dickens N, Mudaliar M, Herzyk P, Vincent I, et al.
PLoS Negl Trop Dis
. 2017 Jun;
11(6):e0005649.
PMID: 28622334
Amphotericin B has emerged as the therapy of choice for use against the leishmaniases. Administration of the drug in its liposomal formulation as a single injection is being promoted in...
9.
Vincent I, Racine G, Legare D, Ouellette M
Proteomes
. 2017 Mar;
3(4):328-346.
PMID: 28248274
Antimony (SbIII) and miltefosine (MIL) are important drugs for the treatment of parasite infections. The mitochondrion is likely to play a central role in SbIII and MIL induced cell death...
10.
Vincent I, Daly R, Courtioux B, Cattanach A, Bieler S, Ndungu J, et al.
PLoS Negl Trop Dis
. 2016 Dec;
10(12):e0005140.
PMID: 27941966
Treatment for human African trypanosomiasis is dependent on the species of trypanosome causing the disease and the stage of the disease (stage 1 defined by parasites being present in blood...