Isabel Karkossa
Overview
Explore the profile of Isabel Karkossa including associated specialties, affiliations and a list of published articles.
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Articles
26
Citations
242
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Recent Articles
11.
Schaffert A, Karkossa I, Ueberham E, Schlichting R, Walter K, Arnold J, et al.
Environ Int
. 2022 May;
164:107279.
PMID: 35567983
The obesity pandemic is presumed to be accelerated by endocrine disruptors such as phthalate-plasticizers, which interfere with adipose tissue function. With the restriction of the plasticizer di-(2-ethylhexyl)-phthalate (DEHP), the search...
12.
Abdolahpur Monikh F, Chupani L, Karkossa I, Gardian Z, Arenas-Lago D, von Bergen M, et al.
NanoImpact
. 2022 May;
22:100315.
PMID: 35559972
Nanomaterials (NMs) taken up from the environment carry a complex ecocorona consisting of dissolved organic matter. An ecocorona is assumed to influence the interactions between NMs and endogenous biomolecules and...
13.
Murthy S, Karkossa I, Schmidt C, Hoffmann A, Hagemann T, Rothe K, et al.
Cell Death Dis
. 2022 Jan;
13(1):53.
PMID: 35022393
The danger signal extracellular calcium is pathophysiologically increased in the synovial fluid of patients with rheumatoid arthritis (RA). Calcium activates the NLRP3-inflammasome via the calcium-sensing receptor in monocytes/macrophages primed by...
14.
Walter K, Grosskopf H, Karkossa I, von Bergen M, Schubert K
Int J Environ Res Public Health
. 2021 Oct;
18(19).
PMID: 34639632
Sensing microbial tryptophan catabolites by the aryl hydrocarbon receptor (AhR) plays a pivotal role in host-microbiome homeostasis by modulating the host immune response. Nevertheless, the involved cellular processes triggered by...
15.
Krieg L, Didt K, Karkossa I, Bernhart S, Kehr S, Subramanian N, et al.
Gut
. 2021 Oct;
71(11):2179-2193.
PMID: 34598978
Objective: Human white adipose tissue (AT) is a metabolically active organ with distinct depot-specific functions. Despite their locations close to the gastrointestinal tract, mesenteric AT and epiploic AT (epiAT) have...
16.
Schaffert A, Arnold J, Karkossa I, Bluher M, von Bergen M, Schubert K
Cells
. 2021 Sep;
10(9).
PMID: 34572016
The use of the plasticizer bis(2-ethylhexyl)phthalate (DEHP) and other plasticizers in the manufacture of plastic products has been restricted due to adverse health outcomes such as obesity, metabolic syndrome, and...
17.
Karkossa I, Bannuscher A, Hellack B, Wohlleben W, Laloy J, Stan M, et al.
Sci Total Environ
. 2021 Aug;
801:149538.
PMID: 34428663
The immense diversity and constant development of nanomaterials (NMs) increase the need for a facilitated risk assessment, which requires knowledge of the modes of action (MoAs) of NMs. This necessitates...
18.
Schaffert A, Krieg L, Weiner J, Schlichting R, Ueberham E, Karkossa I, et al.
Environ Int
. 2021 Jun;
156:106730.
PMID: 34186270
Bisphenol A (BPA), which is used in a variety of consumer-related plastic products, was reported to cause adverse effects, including disruption of adipocyte differentiation, interference with obesity mechanisms, and impairment...
19.
Schubert K, Karkossa I, Schor J, Engelmann B, Steinheuer L, Bruns T, et al.
Front Immunol
. 2021 Jun;
12:616967.
PMID: 34108957
The function of mucosal-associated invariant T (MAIT) cells highly depends on the mode of activation, either by recognition of bacterial metabolites their T cell receptor (TCR) or in a TCR-independent...
20.
Grosskopf H, Walter K, Karkossa I, von Bergen M, Schubert K
Front Immunol
. 2021 Apr;
12:620270.
PMID: 33868237
Emerging studies revealed that the Aryl hydrocarbon receptor (AhR), a receptor sensing environmental contaminants, is executing an immunomodulatory function. However, it is an open question to which extent this is...