Isabel Gamache
Overview
Explore the profile of Isabel Gamache including associated specialties, affiliations and a list of published articles.
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Articles
8
Citations
36
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0
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Recent Articles
1.
De La Barrera S, De La Barrera B, Legault M, Gamache I, Manousaki D
Nutrients
. 2024 Nov;
16(22).
PMID: 39599583
Background/objectives: Nutritional deficiencies have been proposed as possible etiological causes for autoimmune diseases, among which type 1 diabetes (T1D). Vitamin K (VK) has potentially positive effects on type 2 diabetes,...
2.
Yazdanpanah M, Yazdanpanah N, Gamache I, Ong K, Perry J, Manousaki D
Genome Med
. 2024 May;
16(1):69.
PMID: 38802955
Background: The role of metabolism in the variation of age at menarche (AAM) and age at natural menopause (ANM) in the female population is not entirely known. We aimed to...
3.
Richard-St-Hilaire A, Gamache I, Pelletier J, Grenier J, Poujol R, Hussin J
Genome Biol Evol
. 2024 Jan;
16(1).
PMID: 38207129
Cytochromes P450 (CYP450) are hemoproteins generally involved in the detoxification of the body of xenobiotic molecules. They participate in the metabolism of many drugs and genetic polymorphisms in humans have...
4.
Ghanbari F, Otomo N, Gamache I, Iwami T, Koike Y, Khanshour A, et al.
JBMR Plus
. 2023 Dec;
7(12):e10830.
PMID: 38130750
Adolescent idiopathic scoliosis (AIS) is the most common form of pediatric musculoskeletal disorder. Observational studies have pointed to several risk factors for AIS, but almost no evidence exists to support...
5.
Legault M, Barhdadi A, Gamache I, Lemacon A, Lemieux Perreault L, Grenier J, et al.
Genet Epidemiol
. 2023 Jan;
47(2):198-212.
PMID: 36701426
Genetic variants in drug targets can be used to predict the long-term, on-target effect of drugs. Here, we extend this principle to assess how sex and body mass index may...
6.
Mostefai F, Gamache I, NGuessan A, Pelletier J, Huang J, Murall C, et al.
Front Med (Lausanne)
. 2022 Mar;
9:826746.
PMID: 35265640
The genome of the Severe Acute Respiratory Syndrome coronavirus 2 (SARS-CoV-2), the pathogen that causes coronavirus disease 2019 (COVID-19), has been sequenced at an unprecedented scale leading to a tremendous...
7.
Gamache I, Legault M, Grenier J, Sanchez R, Rheaume E, Asgari S, et al.
Elife
. 2021 Oct;
10.
PMID: 34609279
Pharmacogenomic studies have revealed associations between rs1967309 in the adenylyl cyclase type 9 () gene and clinical responses to the cholesteryl ester transfer protein (CETP) modulator dalcetrapib, however, the mechanism...
8.
Ajeawung N, Nguyen T, Lu L, Kucharski T, Rousseau J, Molidperee S, et al.
Am J Hum Genet
. 2019 Jul;
105(3):625-630.
PMID: 31303264
Rothmund-Thomson syndrome (RTS) is an autosomal-recessive disorder characterized by poikiloderma, sparse hair, short stature, and skeletal anomalies. Type 2 RTS, which is defined by the presence of bi-allelic mutations in...