Isabel Cortegano
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Explore the profile of Isabel Cortegano including associated specialties, affiliations and a list of published articles.
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Citations
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Recent Articles
11.
Cortegano I, Rodriguez M, Martin I, Prado M, Ruiz C, Hortiguela R, et al.
Cell Death Dis
. 2017 Aug;
8(8):e3000.
PMID: 28817118
Aging has a strong impact on the activity of the immune system, enhancing susceptibility to pathogens and provoking a predominant pre-inflammatory status, whereas dampening responses to vaccines in humans and...
12.
Rubio-Navarro A, Guerrero-Hue M, Martin-Fernandez B, Cortegano I, Olivares-Alvaro E, de Las Heras N, et al.
J Vis Exp
. 2016 Nov;
(116).
PMID: 27805599
There is increasing evidence suggesting the important role of inflammation and, subsequently, macrophages in the development and progression of renal disease. Macrophages are heterogeneous cells that have been implicated in...
13.
Martin-Fernandez B, Rubio-Navarro A, Cortegano I, Ballesteros S, Alia M, Cannata-Ortiz P, et al.
PLoS One
. 2016 Jan;
11(1):e0145946.
PMID: 26730742
We aimed to evaluate macrophages heterogeneity and structural, functional and inflammatory alterations in rat kidney by aldosterone + salt administration. The effects of treatment with spironolactone on above parameters were...
14.
Prado C, Rodriguez M, Cortegano I, Ruiz C, Alia M, de Andres B, et al.
J Innate Immun
. 2014 Mar;
6(4):499-514.
PMID: 24603602
The diversity in antibody repertoire relies on different B cell populations working efficiently to fulfil distinct specific functions. We recently described an innate-like CD19(+)CD45R(-/lo) (19(+)45R(lo)) cell population in postnatal unstimulated...
15.
de Andres B, Prado C, Palacios B, Alia M, Jagtap S, Serrano N, et al.
J Immunol
. 2012 Jul;
189(5):2300-8.
PMID: 22837485
In the adult spleen, CD19⁺CD45R(-/lo) (19⁺45R(lo)) lymphocytes of embryonic origin exist as a distinct population to that of the conventional B cell lineage. These cells display a plasmablast phenotype, and...
16.
Serrano N, Cortegano I, Ruiz C, Alia M, de Andres B, Rejas M, et al.
Hepatology
. 2012 May;
56(5):1934-45.
PMID: 22611008
Unlabelled: In the mouse embryo, hematopoietic progenitor cells migrate to the fetal liver (FL) between gestational days (E) 9.5 and 10.5, where they rapidly expand to form the main fetal...
17.
A role for DNA polymerase mu in the emerging DJH rearrangements of the postgastrulation mouse embryo
Gozalbo-Lopez B, Andrade P, Terrados G, de Andres B, Serrano N, Cortegano I, et al.
Mol Cell Biol
. 2008 Dec;
29(5):1266-75.
PMID: 19103746
The molecular complexes involved in the nonhomologous end-joining process that resolves recombination-activating gene (RAG)-induced double-strand breaks and results in V(D)J gene rearrangements vary during mammalian ontogeny. In the mouse, the...
18.
de Andres B, Cortegano I, Serrano N, Del Rio B, Martin P, Gonzalo P, et al.
J Immunol
. 2007 Oct;
179(8):5326-34.
PMID: 17911619
Ab responses to selected Ags are produced by discrete B cell populations whose presence and functional relevance vary along the ontogeny. The earliest B lineage-restricted precursors in gestational day 11...
19.
Minguet S, Cortegano I, Gonzalo P, Martinez-Marin J, de Andres B, Salas C, et al.
J Clin Invest
. 2003 Oct;
112(8):1152-63.
PMID: 14561700
Embryo liver morphogenesis takes place after gastrulation and starts with a ventral foregut evagination that reacts to factor signaling from both cardiac mesoderm and septum transversum mesenchyme. Current knowledge of...
20.
Del Pozo V, Rojo M, Rubio M, Cortegano I, Cardaba B, Gallardo S, et al.
Am J Respir Crit Care Med
. 2002 Sep;
166(5):732-7.
PMID: 12204873
The pathophysiology of asthma involves an intricate network of molecular and cellular interactions. Elevated Th2 cytokines (interleukin [IL]-5 and IL-4) associated with eosinophilic inflammation characterize allergic diseases and provide potential...