Isabel Cortegano
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Explore the profile of Isabel Cortegano including associated specialties, affiliations and a list of published articles.
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20
Citations
323
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Recent Articles
1.
Garcia-Caballero C, Guerrero-Hue M, Vallejo-Mudarra M, Palomino Antolin A, Decouty-Perez C, Sanchez-Mendoza L, et al.
Free Radic Biol Med
. 2024 Oct;
225:430-444.
PMID: 39413979
Massive intravascular hemolysis occurs not unfrequently in many clinical conditions. Breakdown of erythrocytes promotes the accumulation of heme-derivates in the kidney, increasing oxidative stress and cell death, thus promoting acute...
2.
Cortegano I, Rodriguez M, Hernangomez S, Arrabal A, Garcia-Vao C, Rodriguez J, et al.
Front Immunol
. 2022 Dec;
13:1011607.
PMID: 36561744
Bronchiolitis in children is associated with significant rates of morbidity and mortality. Many studies have been performed using samples from hospitalized bronchiolitis patients, but little is known about the immunological...
3.
Vazquez-Carballo C, Herencia C, Guerrero-Hue M, Garcia-Caballero C, Rayego-Mateos S, Morgado-Pascual J, et al.
J Pathol
. 2022 Jul;
258(3):236-249.
PMID: 35903022
Massive intravascular hemolysis is a common characteristic of several pathologies. It is associated with the release of large quantities of heme into the circulation, promoting injury in vulnerable organs, mainly...
4.
Vazquez-Carballo C, Guerrero-Hue M, Garcia-Caballero C, Rayego-Mateos S, Opazo-Rios L, Morgado-Pascual J, et al.
Int J Mol Sci
. 2021 Jan;
22(2).
PMID: 33467524
Acute kidney injury (AKI) is an important health problem, affecting 13.3 million individuals/year. It is associated with increased mortality, mainly in low- and middle-income countries, where renal replacement therapy is...
5.
Sanchez-Tarjuelo R, Cortegano I, Manosalva J, Rodriguez M, Ruiz C, Alia M, et al.
Front Immunol
. 2020 Oct;
11:2120.
PMID: 33042124
is the main cause of bacterial pneumonia, a condition that currently produces significant global morbidity and mortality. The initial immune response to this bacterium occurs when the innate system recognizes...
6.
Martinez-Roman P, Lopez-Huertas M, Crespo-Bermejo C, Arca-Lafuente S, Cortegano I, Valle-Millares D, et al.
J Clin Med
. 2020 Jul;
9(7).
PMID: 32635221
Coinfection with hepatitis C virus (HCV) influences HIV reservoir size. However, it is unknown whether this coinfection also induces a higher provirus transcription. Viral transcription is promoted by synergy between...
7.
Rubio-Navarro A, Vazquez-Carballo C, Guerrero-Hue M, Garcia-Caballero C, Herencia C, Gutierrez E, et al.
Front Pharmacol
. 2019 Jul;
10:740.
PMID: 31333462
Massive intravascular hemolysis is associated with acute kidney injury (AKI). Nuclear factor erythroid-2-related factor 2 (Nrf2) plays a central role in the defense against oxidative stress by activating the expression...
8.
Cortegano I, Serrano N, Ruiz C, Rodriguez M, Prado C, Alia M, et al.
Haematologica
. 2018 Dec;
104(9):1853-1865.
PMID: 30573502
Embryonic megakaryopoiesis starts in the yolk sac on gestational day 7.5 as part of the primitive wave of hematopoiesis, and it continues in the fetal liver when this organ is...
9.
Braza M, Conde P, Garcia M, Cortegano I, Brahmachary M, Pothula V, et al.
Am J Transplant
. 2018 Jan;
18(5):1247-1255.
PMID: 29314558
The colony-stimulating factor 1 (CSF1) regulates the differentiation and function of tissue macrophages and determines the outcome of the immune response. The molecular mechanisms behind CSF1-mediated macrophage development remain to...
10.
Rubio-Navarro A, Sanchez-Nino M, Guerrero-Hue M, Garcia-Caballero C, Gutierrez E, Yuste C, et al.
J Pathol
. 2017 Dec;
244(3):296-310.
PMID: 29205354
Recurrent and massive intravascular haemolysis induces proteinuria, glomerulosclerosis, and progressive impairment of renal function, suggesting podocyte injury. However, the effects of haemoglobin (Hb) on podocytes remain unexplored. Our results show...