Isaac K Sundar
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Explore the profile of Isaac K Sundar including associated specialties, affiliations and a list of published articles.
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63
Citations
3460
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Recent Articles
1.
Kaur G, Sundar I, Rahman I
Int J Mol Sci
. 2021 Jun;
22(9).
PMID: 34063608
Cellular senescence and lung aging are associated with the pathogenesis of chronic obstructive pulmonary disease (COPD). COPD progresses with aging, and chronic smoking is the key susceptibility factor in lung...
2.
Wang Q, Sundar I, Lucas J, Muthumalage T, Rahman I
JCI Insight
. 2021 May;
6(12).
PMID: 34014841
Cigarette smoke (CS) is the main etiological factor in the pathogenesis of emphysema/chronic obstructive pulmonary disease (COPD), which is associated with abnormal epithelial-mesenchymal transition (EMT). Previously, we have shown an...
3.
Maremanda K, Sundar I, Li D, Rahman I
Front Pharmacol
. 2020 Oct;
11:584637.
PMID: 33013423
Background: Aging is one of the key contributing factors for chronic obstructive pulmonary diseases (COPD) and other chronic inflammatory lung diseases. Here, we determined how aging contributes to the altered...
4.
Wang Q, Sundar I, Blum J, Ratner J, Lucas J, Chuang T, et al.
Am J Respir Cell Mol Biol
. 2020 Aug;
63(6):794-805.
PMID: 32853043
Electronic-cigarette (e-cig) vaping is a serious concern, as many pregnant women who vape consider it safe. However, little is known about the harmful effects of prenatal e-cig exposure on adult...
5.
Maremanda K, Sundar I, Li D, Rahman I
Res Sq
. 2020 Jul;
PMID: 32702724
Aging is one of the key contributing factors for chronic obstructive pulmonary diseases (COPD) and other chronic inflammatory lung diseases. Cigarette smoke is a major etiological risk factor that has...
6.
Wang Q, Sundar I, Li D, Lucas J, Muthumalage T, McDonough S, et al.
Respir Res
. 2020 Jun;
21(1):154.
PMID: 32552811
Electronic cigarette (e-cig) vaping is increasing rapidly in the United States, as e-cigs are considered less harmful than combustible cigarettes. However, limited research has been conducted to understand the possible...
7.
Manevski M, Muthumalage T, Devadoss D, Sundar I, Wang Q, Singh K, et al.
Redox Biol
. 2020 Feb;
33:101443.
PMID: 32037306
The abnormal inflammatory responses due to the lung tissue damage and ineffective repair/resolution in response to the inhaled toxicants result in the pathological changes associated with chronic respiratory diseases. Investigation...
8.
Wang Q, Khan N, Muthumalage T, Lawyer G, McDonough S, Chuang T, et al.
FASEB Bioadv
. 2019 Dec;
1(10):609-623.
PMID: 31825014
Nicotine inhalation via electronic cigarettes (e-cigs) is an emerging concern. However, little is known about the acute toxicity in the lungs following inhalation of nicotine-containing e-cig aerosols. We hypothesized that...
9.
Sundar I, Maremanda K, Rahman I
Toxicol Lett
. 2019 Oct;
317:92-101.
PMID: 31593750
Cigarette smoke (CS) is known to cause mitochondrial dysfunction leading to cellular senescence in lung cells. We determined the mechanism of mitochondrial dysfunction by CS in lung epithelial cells. CS...
10.
Khan N, Yogeswaran S, Wang Q, Muthumalage T, Sundar I, Rahman I
PLoS One
. 2019 Feb;
14(2):e0211645.
PMID: 30811401
The use of emerging tobacco products, such as waterpipe or hookah and electronic cigarettes (e-cigs), has gained significant popularity and are promoted as safer alternatives to conventional cigarettes. Circadian systems...