Irina Alafuzoff
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Explore the profile of Irina Alafuzoff including associated specialties, affiliations and a list of published articles.
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174
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10793
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Recent Articles
1.
Kovacs G, Grinberg L, Halliday G, Alafuzoff I, Dugger B, Murayama S, et al.
Mov Disord
. 2024 Oct;
39(12):2173-2179.
PMID: 39360851
No abstract available.
2.
Libard S, Tamsen F, Alafuzoff I
Acta Neuropathol
. 2024 Jul;
148(1):13.
PMID: 39085656
It has been suggested that alcohol consumption protects against Parkinson's disease (PD). Here we assessed postmortem tissue samples from the brains and livers of 100 subjects with ages at death...
3.
Libard S, Hodik M, Cesarini K, Dragomir A, Alafuzoff I
J Alzheimers Dis
. 2024 Apr;
99(2):729-737.
PMID: 38669551
Background: Amyloid-β (Aβ) is one of the hallmark lesions of Alzheimer's disease (AD). During the disease process, Aβ undergoes biochemical changes, producing toxic Aβ variants, proposed to be detected within...
4.
Alafuzoff I, Libard S
Int J Mol Sci
. 2024 Apr;
25(7).
PMID: 38612875
Neuropathological assessment was conducted on 1630 subjects, representing 5% of all the deceased that had been sent to the morgue of Uppsala University Hospital during a 15-year-long period. Among the...
5.
Libard S, Alafuzoff I
Neuropathol Appl Neurobiol
. 2023 Jun;
49(4):e12917.
PMID: 37317631
Aims: This study aims to study the association between pancreatic islet amyloid polypeptide (IAPP) and Alzheimer's disease neuropathological change (ADNC) in brain biopsies obtained from subjects with idiopathic normal pressure...
6.
Nelson P, Lee E, Cykowski M, Alafuzoff I, Arfanakis K, Attems J, et al.
Acta Neuropathol
. 2022 Dec;
145(2):159-173.
PMID: 36512061
An international consensus report in 2019 recommended a classification system for limbic-predominant age-related TDP-43 encephalopathy neuropathologic changes (LATE-NC). The suggested neuropathologic staging system and nomenclature have proven useful for autopsy...
7.
Tamsen F, Alafuzoff I
Virchows Arch
. 2022 Nov;
482(4):721-727.
PMID: 36445483
The objective of this study was to assess who is merited an autopsy in Sweden. Data from the Swedish cause of death (COD) registry over a period of 20 years...
8.
Libard S, Giedraitis V, Kilander L, Ingelsson M, Alafuzoff I
J Alzheimers Dis
. 2022 Oct;
90(4):1601-1614.
PMID: 36314207
Background: There are more than 300 presenilin-1 (PSEN1) mutations identified but a thorough postmortem neuropathological assessment of the mutation carriers is seldom performed. Objective: To assess neuropathological changes (NC) in...
9.
Gastrointestinal Biopsy Obtained During Cancer Screening, a Biological Marker for α-Synucleinopathy?
Jotanovic J, Milin-Lazovic J, Alafuzoff I
J Neuropathol Exp Neurol
. 2022 Apr;
81(5):356-362.
PMID: 35388426
The hallmark alteration in α-synucleinopathies, α-synuclein, is observed not only in the brain but also in the peripheral tissues, particularly in the intestine. This suggests that endoscopic biopsies performed for...
10.
Pagnon de la Vega M, Giedraitis V, Michno W, Kilander L, Guner G, Zielinski M, et al.
Sci Transl Med
. 2021 Aug;
13(606).
PMID: 34380771
Point mutations in the amyloid precursor protein gene () cause familial Alzheimer's disease (AD) by increasing generation or altering conformation of amyloid β (Aβ). Here, we describe the mutation (Δ690-695),...