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Irina-Iuliana Costache

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Articles 35
Citations 218
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Recent Articles
1.
Badescu M, Badulescu O, Costache A, Mitu O, Lupu V, Dmour B, et al.
Life (Basel) . 2023 Nov; 13(11). PMID: 38004361
Advances in the treatment of hemophilia have increased the life expectancy of this population and we are currently facing diseases associated with aging, including cardiovascular ones. Coronary atherosclerosis, with acute...
2.
Honceriu C, Roca M, Costache A, Abalasei B, Popescu L, Puni A, et al.
Medicina (Kaunas) . 2023 Oct; 59(10). PMID: 37893444
: Cortisol is a valuable marker for assessing the body's response to any form of stress. We conducted this study in order to evaluate the variations of salivary and serum...
3.
Jigoranu R, Roca M, Costache A, Mitu O, Oancea A, Miftode R, et al.
Life (Basel) . 2023 Aug; 13(8). PMID: 37629496
Atherosclerosis is a significant health concern with a growing incidence worldwide. It is directly linked to an increased cardiovascular risk and to major adverse cardiovascular events, such as acute coronary...
4.
Duca S, Roca M, Costache A, Chetran A, Afrasanie I, Miftode R, et al.
Life (Basel) . 2023 May; 13(5). PMID: 37240799
Myocardial ischemia is a pathophysiological state characterized by inadequate perfusion of the myocardium, resulting in an imbalance between myocardial oxygen demand and supply. It is most commonly caused by coronary...
5.
Miftode R, Costache I, Constantinescu D, Mitu O, Timpau A, Hancianu M, et al.
Life (Basel) . 2023 Apr; 13(4). PMID: 37109427
(1) Background: Acute heart failure (HF) represents a complex clinical syndrome burdened by increased mortality and a high rate of systemic complications. Although natriuretic peptides (e.g., NT-proBNP) currently represent the...
6.
Badescu M, Sorodoc V, Lionte C, Ouatu A, Haliga R, Costache A, et al.
J Pers Med . 2023 Jan; 13(1). PMID: 36675819
In recent years, direct oral anticoagulants (DOAC) have accumulated evidence of efficacy and safety in various clinical scenarios and are approved for a wide spectrum of indications. Still, they are...
7.
Timpau A, Miftode R, Costache I, Petris A, Miftode I, Gheorghe L, et al.
Antibiotics (Basel) . 2023 Jan; 12(1). PMID: 36671345
Background: Literature data on bacterial infections and their impact on the mortality rates of COVID-19 patients from Romania are scarce, while worldwide reports are contrasting. 2. Materials And Methods: We...
8.
Mitu I, Dimitriu C, Preda C, Mitu O, Costache I, Miftode R, et al.
Metabolites . 2022 Dec; 12(12). PMID: 36557255
This research focused on establishing a hierarchy concerning the influence of various biological markers and body composition parameters on preventing, diagnosing and managing Metabolic Syndrome (MetS). Our cross-sectional cohort study...
9.
Miftode R, Constantinescu D, Cianga C, Petris A, Costache I, Mitu O, et al.
Life (Basel) . 2022 Dec; 12(12). PMID: 36556311
(1) Background: Acute heart failure (HF) represents one of the most common yet extremely severe presentations in emergency services worldwide, requiring prompt diagnosis, followed by an adequate therapeutic approach, and...
10.
Costache A, Leon-Constantin M, Roca M, Mastaleru A, Anghel R, Zota I, et al.
J Cardiovasc Dev Dis . 2022 Dec; 9(12). PMID: 36547450
Sustained physical activity induces morphological and functional changes in the cardiovascular system. While mostly physiological, they can also become a trigger for major adverse cardiovascular events, the most severe of...