Direct Oral Anticoagulants for Stroke and Systemic Embolism Prevention in Patients with Left Ventricular Thrombus

Overview

Journal J Pers Med

Date 2023 Jan 21

PMID 36675819

Authors

Minerva Codruta Badescu

Victorita Sorodoc

Catalina Lionte

Anca Ouatu

Raluca Ecaterina Haliga

Alexandru Dan Costache

Oana Nicoleta Buliga-Finis

Ioan Simon

Laurentiu Sorodoc

Irina-Iuliana Costache

Ciprian Rezus

Affiliations

Soon will be listed here.

Abstract

In recent years, direct oral anticoagulants (DOAC) have accumulated evidence of efficacy and safety in various clinical scenarios and are approved for a wide spectrum of indications. Still, they are currently used off-label for left ventricular thrombus owing to a paucity of evidence. For the same reason, there is a lack of guideline indication as well. Our work is based on an exhaustive analysis of the available literature and provides a structured and detailed update on the use of DOACs in patients with left ventricle thrombus. The safety and efficacy of DOACs were analyzed in particular clinical scenarios. As far as we know, this is the first paper that analyzes DOACs in this approach.

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