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Iraia Garcia-Santisteban

Explore the profile of Iraia Garcia-Santisteban including associated specialties, affiliations and a list of published articles. Areas
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Articles 19
Citations 306
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Recent Articles
1.
Cilleros-Portet A, Lesseur C, Mari S, Cosin-Tomas M, Lozano M, Irizar A, et al.
Nat Commun . 2025 Mar; 16(1):2431. PMID: 40087310
Increasing evidence supports the role of the placenta in neurodevelopment and in the onset of neuropsychiatric disorders. Recently, mQTL and iQTL maps have proven useful in understanding relationships between SNPs...
2.
Hernangomez-Laderas A, Cilleros-Portet A, Martinez Velasco S, Mari S, Legarda M, Gonzalez-Garcia B, et al.
Biol Sex Differ . 2023 Dec; 14(1):86. PMID: 38072919
Background: Celiac disease (CeD) is an immune-mediated disorder that develops in genetically predisposed individuals upon gluten consumption. HLA risk alleles explain 40% of the genetic component of CeD, so there...
3.
Gonzalez-Garcia B, Mari S, Cilleros-Portet A, Hernangomez-Laderas A, Fernandez-Jimenez N, Garcia-Santisteban I, et al.
Front Immunol . 2023 Jul; 14:1082862. PMID: 37457693
Background: Celiac Disease (CeD) is an autoimmune disorder triggered by gluten intake in genetically susceptible individuals. Highest risk individuals are homozygous for the Human Leucocyte Antigen (HLA) DQ2.5 haplotype or...
4.
Cilleros-Portet A, Lesseur C, Mari S, Cosin-Tomas M, Lozano M, Irizar A, et al.
medRxiv . 2023 Mar; PMID: 36945560
Increasing evidence supports the role of placenta in neurodevelopment and potentially, in the later onset of neuropsychiatric disorders. Recently, methylation quantitative trait loci (mQTL) and interaction QTL (iQTL) maps have...
5.
Rueda-Martinez A, Garitazelaia A, Cilleros-Portet A, Mari S, Arauzo R, de Miguel J, et al.
Int J Mol Sci . 2021 Jul; 22(11). PMID: 34199930
Endometriosis is a common gynecological disorder that has been associated with endometrial, breast and epithelial ovarian cancers in epidemiological studies. Since complex diseases are a result of multiple environmental and...
6.
Garcia-Santisteban I, Romero-Garmendia I, Cilleros-Portet A, Bilbao J, Fernandez-Jimenez N
Int Rev Cell Mol Biol . 2021 Mar; 358:1-45. PMID: 33707051
Celiac Disease (CeD) is an immune-mediated complex disease that is triggered by the ingestion of gluten and develops in genetically susceptible individuals. It has been known for a long time...
7.
Garcia-Santisteban I, Llopis A, Krenning L, Vallejo-Rodriguez J, van den Broek B, Zubiaga A, et al.
BMC Biol . 2021 Feb; 19(1):35. PMID: 33607997
Background: The G1 checkpoint is a critical regulator of genomic stability in untransformed cells, preventing cell cycle progression after DNA damage. DNA double-strand breaks (DSBs) recruit and activate ATM, a...
8.
Olazagoitia-Garmendia A, Zhang L, Mera P, Godbout J, Sebastian-delaCruz M, Garcia-Santisteban I, et al.
Gut . 2021 Feb; 71(1):68-76. PMID: 33526437
Objectives: Coeliac disease (CD) is a complex autoimmune disorder that develops in genetically susceptible individuals. Dietary gluten triggers an immune response for which the only available treatment so far is...
9.
Garitazelaia A, Rueda-Martinez A, Arauzo R, de Miguel J, Cilleros-Portet A, Mari S, et al.
Life (Basel) . 2021 Jan; 11(1). PMID: 33401535
Endometriosis, one of the most common gynecological disorders, is a complex disease characterized by the growth of endometrial-like tissue in extra-uterine locations and is a cause of pelvic pain and...
10.
Garcia-Santisteban I, Cilleros-Portet A, Moyua-Ormazabal E, Kurilshikov A, Zhernakova A, Garcia-Etxebarria K, et al.
Nutrients . 2020 May; 12(5). PMID: 32423041
Celiac disease (CeD) is a complex immune-mediated inflammatory condition triggered by the ingestion of gluten in genetically predisposed individuals. Literature suggests that alterations in gut microbiota composition and function precede...