Ionita C Ghiran
Overview
Explore the profile of Ionita C Ghiran including associated specialties, affiliations and a list of published articles.
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Articles
24
Citations
375
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Recent Articles
1.
Yang M, Hancco Zirena I, Kennedy Q, Patel A, Merrill-Skoloff G, Sack K, et al.
J Thromb Haemost
. 2025 Feb;
PMID: 39952360
Background: Both protein disulfide isomerase (PDI) and SARS-CoV-2 main protease (M) are reliant on active-site cysteines stabilized by adjacent amino acids. We reasoned that redox-active compounds might interfere with both...
2.
Furuhashi K, Kakiuchi M, Ueda R, Oda H, Ummarino S, Ebralidze A, et al.
Nature
. 2025 Jan;
638(8049):206-215.
PMID: 39743593
Stem cells reside in specialized microenvironments, termed niches, at several different locations in tissues. The differential functions of heterogeneous stem cells and niches are important given the increasing clinical applications...
3.
Su X, Junior G, Marie A, Gregus M, Figueroa-Navedo A, Ghiran I, et al.
J Extracell Vesicles
. 2024 Dec;
13(12):e70024.
PMID: 39641316
The study introduces a charge-based fractionation method for fractionating plasma-derived extracellular vesicles (EVs) into sub-populations aimed at the improved purification from free plasma proteins to enhance the diagnostic potential of...
4.
Tran V, de Oliveira-Jr G, Chidester S, Lu S, Pleet M, Ivanov A, et al.
J Extracell Biol
. 2024 Oct;
3(10):e70008.
PMID: 39440167
Circulating RNAs have been investigated systematically for over 20 years, both as constituents of circulating extracellular vesicles (EVs) or, more recently, non-EV RNA carriers, such as exomeres and supermeres. The...
5.
Okeoma C, Premadasa L, Tan C, Ghiran I, Mohan M
bioRxiv
. 2024 Oct;
PMID: 39416016
Background: Epitranscriptomic modifications modulate diverse biological processes like regulation of gene expression, abundance, location and function. N6-methyladenosine (m A) methylation has been shown to regulate various diseases, including cancer and...
6.
Junior G, Welsh J, Pinckney B, Palu C, Lu S, Zimmerman A, et al.
J Extracell Biol
. 2023 Nov;
2(11).
PMID: 37942280
Extracellular vesicles (EVs) are membrane-bound structures released by cells and tissues into biofluids, involved in cell-cell communication. In humans, circulating red blood cells (RBCs), represent the most common cell-type in...
7.
Li G, Chen T, Dahlman J, Eniola-Adefeso L, Ghiran I, Kurre P, et al.
J Extracell Vesicles
. 2023 Feb;
12(2):e12305.
PMID: 36775986
Extracellular vesicles (EVs) carry diverse bioactive components including nucleic acids, proteins, lipids and metabolites that play versatile roles in intercellular and interorgan communication. The capability to modulate their stability, tissue-specific...
8.
Oliveira-Jr G, Barbosa R, Thompson L, Pinckney B, Murphy-Thornley M, Lu S, et al.
Biosens Bioelectron
. 2021 Jun;
189:113307.
PMID: 34062334
MicroRNAs are short, non-coding RNA sequences involved in gene expression regulation. Quantification of miRNAs in biological fluids involves time consuming and laborious methods such as Northern blotting or PCR-based techniques....
9.
Saha K, Sontheimer E, Brooks P, Dwinell M, Gersbach C, Liu D, et al.
Nature
. 2021 Apr;
592(7853):195-204.
PMID: 33828315
The move from reading to writing the human genome offers new opportunities to improve human health. The United States National Institutes of Health (NIH) Somatic Cell Genome Editing (SCGE) Consortium...
10.
Nelson B, Maragh S, Ghiran I, Jones J, DeRose P, Elsheikh E, et al.
Nanomedicine (Lond)
. 2020 Sep;
15(22):2149-2170.
PMID: 32885720
Extracellular vesicles (EVs), such as exosomes and microvesicles, are nonreplicating lipid bilayer particles shed by most cell types which have the potential to revolutionize the development and efficient delivery of...