Ioannis Tikas
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Explore the profile of Ioannis Tikas including associated specialties, affiliations and a list of published articles.
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12
Citations
63
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Recent Articles
1.
Kotoula V, Papadopoulou K, Tikas I, Fostira F, Vrettou E, Chrisafi S, et al.
Breast Cancer
. 2021 Jul;
28(6):1367-1382.
PMID: 34304347
Purpose: The genomic status of non-malignant tissues from carriers of pathogenic germline BRCA1/2 (gBRCA1/2) variants may reveal information towards individualized prophylaxis. We performed spatiotemporal tissue genotype comparisons in a real-life...
2.
Fountzilas E, Kotoula V, Koliou G, Liontos M, Papadopoulou K, Giannoulatou E, et al.
Front Oncol
. 2021 Jun;
11:683057.
PMID: 34141624
Clinical Trial Registration: [ClinicalTrials.gov], identifier [NCT04716374].
3.
Fountzilas E, Kotoula V, Koliou G, Giannoulatou E, Gogas H, Papadimitriou C, et al.
Oncotarget
. 2020 Feb;
11(1):1-14.
PMID: 32002119
We evaluated the association between pathogenic mutations and overall survival (OS) in patients with cancer referred to Hellenic Cooperative Oncology Group-affiliated Departments. Patients referred from 12/1980 to 1/2017 had molecular...
4.
Razis E, Kotoula V, Koliou G, Papadopoulou K, Vrettou E, Giannoulatou E, et al.
Transl Oncol
. 2020 Jan;
13(2):346-354.
PMID: 31891871
Background: High grade glioma molecular profiling is of particular interest in neurooncology. The role of telomerase reverse transcriptase (TERT) varies dependent upon other molecular parameters. We explored the role of...
5.
Zarkavelis G, Kotoula V, Kolliou G, Papadopoulou K, Tikas I, Karavasilis V, et al.
ESMO Open
. 2019 Nov;
4(5):e000525.
PMID: 31673425
Pancreatic cancer is one of the most fatal malignancies ranking fourth among the leading causes of cancer death with diagnosis at late stages carrying a dismal prognosis. The aim of...
6.
Kotoula V, Tsakiri K, Koliou G, Lazaridis G, Papadopoulou K, Giannoulatou E, et al.
Clin Breast Cancer
. 2018 Dec;
19(2):113-125.e4.
PMID: 30545790
Background: We examined tumor genotype characteristics of human epidermal growth factor receptor 2 (HER2)-positive relapsed (R-) and de novo (dn-) metastatic breast cancer (MBC) in trastuzumab-treated patients who were previously...
7.
Fountzilas E, Kotoula V, Tikas I, Manousou K, Papadopoulou K, Poulios C, et al.
Oncotarget
. 2018 Nov;
9(86):35623-35638.
PMID: 30479693
Background: We explored the clinical significance of tumor genotypes and immunophenotypes in non-metastatic colorectal cancer (CRC). Methods: In primary tumors (paraffin blocks) from 412 CRC patients treated with adjuvant chemotherapy,...
8.
Kotoula V, Lakis S, Tikas I, Giannoulatou E, Lazaridis G, Papadopoulou K, et al.
Gynecol Oncol
. 2018 Nov;
152(2):375-386.
PMID: 30446274
Background: Tissue genomic heterogeneity (t-HET) in patients with epithelial ovarian cancer (OVCA) is related to tissue plasticity, i.e., flexibility to adapt to adverse molecular environments. Here, we interrogated the presence...
9.
Pentheroudakis G, Kotoula V, Koliou G, Karavasilis V, Samantas E, Aravantinos G, et al.
Clin Colorectal Cancer
. 2018 Jul;
17(4):e631-e637.
PMID: 29980490
Background: The efficacy and safety of the FOLFIRI (leucovorin, 5-fluorouracil, irinotecan, and oxaliplatin) regimen combined with aflibercept has not been studied in the first-line management of patients with metastatic colorectal...
10.
Papadopoulou K, Murray S, Manousou K, Tikas I, Dervenis C, Sgouros J, et al.
Am J Cancer Res
. 2018 Feb;
8(1):2-15.
PMID: 29416916
Biliary tract cancer (BTC) represents a heterogeneous disease with dismal outcome. Herein, we examined genotype and angiogenesis features in BTC. We applied genotyping (Sanger, qPCR, 101-gene panel NGS), mRNA relative...