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Insaf Filali

Explore the profile of Insaf Filali including associated specialties, affiliations and a list of published articles. Areas
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Articles 6
Citations 37
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Recent Articles
1.
El Hafi M, Anouar E, Lahmidi S, Boulhaoua M, Loubidi M, Alanazi A, et al.
Molecules . 2024 Nov; 29(21). PMID: 39519663
Four new pyrazolo[3,4-]pyrimidines (-) were successfully synthesized in good relative yields by reacting 3-methyl-1-phenyl-1H-pyrazolo[3,4-]pyrimidin-4-ol with various alkylating agents (methyl iodide, propargyl bromide, and phenacyl bromide) at room temperature in DMF...
2.
Baccari W, Saidi I, Filali I, Znati M, Lazrag H, Tounsi M, et al.
RSC Adv . 2024 Feb; 14(7):4654-4665. PMID: 38318626
Despite all the significant progresses made to enhance the efficacy of the existing bank of drugs used to manage and cure type II diabetes mellitus, there is still a need...
3.
Znati M, Filali I, Jabrane A, Casanova J, Bouajila J, Ben Jannet H
Chem Biodivers . 2016 Sep; 14(1). PMID: 27638478
Essential oil of the seeds from the endemic Tunisian plant Ferula tunetana Pomel ex Batt. was analyzed for its chemical composition and screened for its antimicrobial, antioxidant and antigerminative properties....
4.
Filali I, Belkacem M, Ben Nejma A, Souchard J, Ben Jannet H, Bouajila J
J Enzyme Inhib Med Chem . 2016 Mar; 31(sup1):23-33. PMID: 27028352
We synthesized two series of new hydrazide harmine derivatives. The reaction of harmine 1 with ethyl acetate chloride afforded the corresponding ethyl ester 2. The treatment of 2 with hydrazine...
5.
Filali I, Romdhane A, Znati M, Jannet H, Bouajila J
Med Chem . 2015 Sep; 12(2):184-90. PMID: 26362768
Harmine 1 was extracted from the seeds of Peganum harmala. From this natural molecule, a new series of isoxazole derivatives with complete regiospecificity were prepared using 1,3-dipolar cycloaddition reactions with...
6.
Filali I, Bouajila J, Znati M, Bousejra-El Garah F, Ben Jannet H
J Enzyme Inhib Med Chem . 2014 Jul; 30(3):371-6. PMID: 25068731
In our study, a series of new harmine derivatives has been prepared by cycloaddition reaction using various arylnitrile oxides and evaluated in vitro against acetylcholinesterase and 5-lipoxygenase enzymes, MCF7 and...