Ines G Harper
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Explore the profile of Ines G Harper including associated specialties, affiliations and a list of published articles.
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5
Citations
127
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Recent Articles
1.
Harper I, Gjorgjimajkoska O, Siu J, Parmar J, Mulder A, Claas F, et al.
Am J Transplant
. 2018 Dec;
19(5):1371-1379.
PMID: 30548563
Tissue resident lymphocytes are present within many organs, and are presumably transferred at transplantation, but their impact on host immunity is unclear. Here, we examine whether transferred donor natural regulatory...
2.
Augmentation of Recipient Adaptive Alloimmunity by Donor Passenger Lymphocytes within the Transplant
Harper I, Ali J, Harper S, Wlodek E, Alsughayyir J, Negus M, et al.
Cell Rep
. 2016 May;
15(6):1214-27.
PMID: 27134179
Chronic rejection of solid organ allografts remains the major cause of transplant failure. Donor-derived tissue-resident lymphocytes are transferred to the recipient during transplantation, but their impact on alloimmunity is unknown....
3.
Ali J, Negus M, Conlon T, Harper I, Qureshi M, Motallebzadeh R, et al.
Cell Rep
. 2016 Jan;
14(5):1232-1245.
PMID: 26804905
MHC alloantigen is recognized by two pathways: "directly," intact on donor cells, or "indirectly," as self-restricted allopeptide. The duration of each pathway, and its relative contribution to allograft vasculopathy, remain...
4.
Harper S, Ali J, Wlodek E, Negus M, Harper I, Chhabra M, et al.
Proc Natl Acad Sci U S A
. 2015 Oct;
112(41):12788-93.
PMID: 26420874
Adaptive CD8 T-cell immunity is the principal arm of the cellular alloimmune response, but its development requires help. This can be provided by CD4 T cells that recognize alloantigen "indirectly,"...
5.
Harper S, Gelson W, Harper I, Alexander G, Gibbs P
Transplantation
. 2011 Apr;
91(1):128-32.
PMID: 21452417
Background: Sirolimus is unlicensed for use in liver transplantation because of concerns over safety, particularly in regard to hepatic artery thrombosis and excess mortality. However, sirolimus offers potential advantages over...