Kourosh Saeb-Parsy
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Explore the profile of Kourosh Saeb-Parsy including associated specialties, affiliations and a list of published articles.
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111
Citations
8354
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Recent Articles
1.
Yang J, Yamashita-Kanemaru Y, Morris B, Contursi A, Trajkovski D, Xu J, et al.
Nature
. 2025 Mar;
PMID: 40044852
Metastasis is the spread of cancer cells from primary tumours to distant organs and is the cause of 90% of cancer deaths globally. Metastasizing cancer cells are uniquely vulnerable to...
2.
Kandror E, Wang A, Carriere M, Peterson A, Liao W, Tjarnberg A, et al.
bioRxiv
. 2025 Jan;
PMID: 39829819
Here, we report the spatial organization of RNA transcription and associated enhancer dynamics in the human spinal cord at single-cell and single-molecule resolution. We expand traditional multiomic measurements to reveal...
3.
Oliver A, Huang N, Bartolome-Casado R, Li R, Koplev S, Nilsen H, et al.
Nature
. 2024 Nov;
635(8039):699-707.
PMID: 39567783
The gastrointestinal tract is a multi-organ system crucial for efficient nutrient uptake and barrier immunity. Advances in genomics and a surge in gastrointestinal diseases has fuelled efforts to catalogue cells...
4.
Herms A, Fernandez-Antoran D, Alcolea M, Kalogeropoulou A, Banerjee U, Piedrafita G, et al.
Nat Genet
. 2024 Sep;
56(10):2158-2173.
PMID: 39313617
Aging epithelia are colonized by somatic mutations, which are subjected to selection influenced by intrinsic and extrinsic factors. The lack of suitable culture systems has slowed the study of this...
5.
Mareckova M, Garcia-Alonso L, Moullet M, Lorenzi V, Petryszak R, Sancho-Serra C, et al.
Nat Genet
. 2024 Aug;
56(9):1925-1937.
PMID: 39198675
The complex and dynamic cellular composition of the human endometrium remains poorly understood. Previous endometrial single-cell atlases profiled few donors and lacked consensus in defining cell types. We introduce the...
6.
Coppard V, Szep G, Georgieva Z, Howlett S, Jarvis L, Rainbow D, et al.
Front Immunol
. 2024 Aug;
15:1425488.
PMID: 39086484
As the dimensionality, throughput and complexity of cytometry data increases, so does the demand for user-friendly, interactive analysis tools that leverage high-performance machine learning frameworks. Here we introduce FlowAtlas: an...
7.
Gribben C, Galanakis V, Calderwood A, Williams E, Chazarra-Gil R, Larraz M, et al.
Nature
. 2024 May;
630(8015):166-173.
PMID: 38778114
For many adult human organs, tissue regeneration during chronic disease remains a controversial subject. Regenerative processes are easily observed in animal models, and their underlying mechanisms are becoming well characterized,...
8.
Jones R, Gruszczyk A, Schmidt C, Hammersley D, Mach L, Lee M, et al.
Nat Cardiovasc Res
. 2024 Apr;
2(8):733-745.
PMID: 38666037
Recurrent myocardial ischemia can lead to left ventricular (LV) dysfunction in patients with coronary artery disease (CAD). In this observational cohort study, we assessed for chronic metabolomic and transcriptomic adaptations...
9.
Kedlian V, Wang Y, Liu T, Chen X, Bolt L, Tudor C, et al.
Nat Aging
. 2024 Apr;
4(5):727-744.
PMID: 38622407
Skeletal muscle aging is a key contributor to age-related frailty and sarcopenia with substantial implications for global health. Here we profiled 90,902 single cells and 92,259 single nuclei from 17...
10.
Asowata E, Romoli S, Sargeant R, Tan J, Hoffmann S, Huang M, et al.
Kidney Int
. 2024 Mar;
106(1):85-97.
PMID: 38431215
Despite the recent advances in our understanding of the role of lipids, metabolites, and related enzymes in mediating kidney injury, there is limited integrated multi-omics data identifying potential metabolic pathways...