Indira V Subramanian
Overview
Explore the profile of Indira V Subramanian including associated specialties, affiliations and a list of published articles.
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Articles
9
Citations
489
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0
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Recent Articles
1.
Joshi H, Subramanian I, Schnettler E, Ghosh G, Rupaimoole R, Evans C, et al.
Proc Natl Acad Sci U S A
. 2014 Apr;
111(14):5331-6.
PMID: 24706848
Hypoxia-driven changes in the tumor microenvironment facilitate cancer metastasis. In the present study, we investigated the regulatory cross talk between endocytic pathway, hypoxia, and tumor metastasis. Dynamin 2 (DNM2), a...
2.
Jing Y, Lu H, Wu K, Subramanian I, Ramakrishnan S
Int J Cancer
. 2011 Jan;
129(3):751-61.
PMID: 21225621
Previous studies have shown that a single point mutation in endostatin at position 125 (P125A) can improve the biological activity of endostatin. Addition of an integrin-targeting moiety, R-G-D, resulted in...
3.
Ghosh G, Subramanian I, Adhikari N, Zhang X, Joshi H, Basi D, et al.
J Clin Invest
. 2010 Oct;
120(11):4141-54.
PMID: 20972335
Adaptive changes to oxygen availability are critical for cell survival and tissue homeostasis. Prolonged oxygen deprivation due to reduced blood flow to cardiac or peripheral tissues can lead to myocardial...
4.
Subramanian I, Fernandes B, Robinson T, Koening J, Lapara K, Ramakrishnan S
J Cardiovasc Transl Res
. 2010 Jun;
2(1):81-92.
PMID: 20559971
The transplantation of skeletal myoblasts is being tested in various organ systems to facilitate tissue repair and regeneration. Previous studies have indicated that transplanted cells for varied reasons were not...
5.
Nguyen T, Subramanian I, Xiao X, Ghosh G, Nguyen P, Kelekar A, et al.
J Cell Mol Med
. 2009 Mar;
13(9B):3687-98.
PMID: 19298526
Endostatin is a well-characterized endogenous inhibitor of angiogenesis that affects cell proliferation and migration by inhibiting integrin and Wnt-mediated signalling pathways. Here, we show that endothelial cells treated with native...
6.
Ramakrishnan S, Nguyen T, Subramanian I, Kelekar A
Autophagy
. 2007 Jul;
3(5):512-5.
PMID: 17643071
Angiogenesis, the process by which new blood vessels are formed is critical for embryonic development and physiological functioning of normal tissues. Angiogenesis also plays a critical role in the pathology...
7.
Schumacher J, Dings R, Cosin J, Subramanian I, Auersperg N, Ramakrishnan S
Cancer Res
. 2007 Apr;
67(8):3683-90.
PMID: 17440080
Vascular endothelial growth factor (VEGF) expression correlates with microvessel density, stage, malignant ascites, metastasis, and survival in ovarian cancer. By transducing VEGF165 into a nontumorigenic rat ovarian surface epithelial cell...
8.
Nguyen T, Subramanian I, Kelekar A, Ramakrishnan S
Blood
. 2007 Feb;
109(11):4793-802.
PMID: 17272502
Inhibition of endothelial cell proliferation and angiogenesis is emerging as an important strategy in cancer therapeutics. Kringle 5 (K5) of human plasminogen is a potent angiogenesis inhibitor. Previous studies have...
9.
Subramanian I, Nguyen T, Truskinovsky A, Tolar J, Blazar B, Ramakrishnan S
Cancer Res
. 2006 Apr;
66(8):4319-28.
PMID: 16618757
A human ovarian cancer cell line, which migrates to mouse ovaries and establishes peritoneal carcinomatosis, was used to evaluate the cooperative effect of an antiangiogenic gene therapy combined with chemotherapy....