Imke Atreya
Overview
Explore the profile of Imke Atreya including associated specialties, affiliations and a list of published articles.
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Articles
69
Citations
1249
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Recent Articles
1.
Atreya I, Neurath M
Signal Transduct Target Ther
. 2024 Jun;
9(1):156.
PMID: 38851767
No abstract available.
2.
Sommer K, Garibagaoglu H, Paap E, Wiendl M, Muller T, Atreya I, et al.
Cells
. 2024 May;
13(10.
PMID: 38786041
Monocytes, as well as downstream macrophages and dendritic cells, are essential players in the immune system, fulfilling key roles in homeostasis as well as in inflammatory conditions. Conventionally, driven by...
3.
Wiendl M, Dedden M, Liu L, Schweda A, Paap E, Ullrich K, et al.
Nat Commun
. 2024 Feb;
15(1):1043.
PMID: 38310086
Despite promising preclinical and earlier clinical data, a recent phase III trial on the anti-β7 integrin antibody etrolizumab in Crohn's disease (CD) did not reach its primary endpoint. The mechanisms...
4.
Schramm S, Liu L, Saad M, Dietz L, Dedden M, Muller T, et al.
J Crohns Colitis
. 2024 Jan;
18(7):1162-1172.
PMID: 38243565
Background And Aims: The G protein coupled receptor GPR15 is expressed on and functionally important for T cells homing to the large intestine. However, the precise mechanisms by which GPR15...
5.
Schulz-Kuhnt A, Ruhle K, Javidmehr A, Dobronti M, Biwank J, Knittel S, et al.
Gut
. 2024 Jan;
73(4):601-612.
PMID: 38176897
Objective: Mucosal T cells play a major role in inflammatory bowel disease (IBD). However, their immunometabolism during intestinal inflammation is poorly understood. Due to its impact on cellular metabolism and...
6.
Ullrich K, Derdau J, Baltes C, Battistella A, Rosso G, Uderhardt S, et al.
Gut
. 2023 Aug;
72(11):2081-2094.
PMID: 37541770
IL-3 has been reported to be involved in various inflammatory disorders, but its role in inflammatory bowel disease (IBD) has not been addressed so far. Here, we determined IL-3 expression...
7.
Schulze L, Becker E, Dedden M, Liu L, van Passen C, Mohamed-Abdou M, et al.
J Crohns Colitis
. 2023 May;
17(11):1817-1832.
PMID: 37208197
Background And Aims: The anti-MAdCAM-1 antibody ontamalimab demonstrated efficacy in a phase II trial in ulcerative colitis and results of early terminated phase III trials are pending, but its precise...
8.
Muller T, Liu L, Czerwinski T, Wiesinger M, Dedden M, Paap E, et al.
Cell Mol Gastroenterol Hepatol
. 2023 Apr;
16(1):183-187.e2.
PMID: 37085136
No abstract available.
9.
Sommer K, Heidbreder K, Kreiss L, Dedden M, Paap E, Wiendl M, et al.
Clin Transl Med
. 2023 Apr;
13(4):e1233.
PMID: 37029786
Background: Closing mucosal defects to reach mucosal healing is an important goal of therapy in inflammatory bowel disease (IBD). Among other cells, monocyte-derived macrophages are centrally involved in such intestinal...
10.
Heidbreder K, Sommer K, Wiendl M, Muller T, Atreya I, Hildner K, et al.
Front Immunol
. 2023 Feb;
13:1040775.
PMID: 36741412
Introduction: Macrophages play an important role in intestinal wound healing. However, the trajectories from circulating monocytes to gut macrophages are incompletely understood. Methods: Taking advantage of mice depleted for non-classical...