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Imee M A Del Mundo

Explore the profile of Imee M A Del Mundo including associated specialties, affiliations and a list of published articles. Areas
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Articles 4
Citations 19
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Recent Articles
1.
Zewail-Foote M, Del Mundo I, Klattenhoff A, Vasquez K
Nucleic Acids Res . 2025 Feb; 53(4). PMID: 39970277
Genetic instability is a hallmark of cancer, and mutation hotspots in human cancer genomes co-localize with alternative DNA structure-forming sequences (e.g. H-DNA), implicating them in cancer etiology. H-DNA has been...
2.
Zewail-Foote M, Del Mundo I, Klattenhoff A, Vasquez K
Nucleic Acids Res . 2025 Feb; 53(4). PMID: 39950343
Genetic instability is a hallmark of cancer, and mutation hotspots in human cancer genomes co-localize with alternative DNA structure-forming sequences (e.g. H-DNA), implicating them in cancer etiology. H-DNA has been...
3.
Xu Q, Del Mundo I, Zewail-Foote M, Luke B, Vasquez K, Kowalski J
Brief Bioinform . 2024 Mar; 25(2). PMID: 38521050
Sequence-level data offers insights into biological processes through the interaction of two or more genomic features from the same or different molecular data types. Within motifs, this interaction is often...
4.
Del Mundo I, Cho E, Dalby K, Vasquez K
Chem Commun (Camb) . 2020 Jan; 56(13):1996-1999. PMID: 31960843
Here, we developed a coralyne-based, 'light-up' intercalator displacement assay to identify molecular stabilizers of triplex DNA using a sequence from a chromosomal breakpoint hotspot in the human c-MYC oncogene. Its...
5.
Del Mundo I, Vasquez K, Wang G
Biochim Biophys Acta Mol Cell Res . 2019 Sep; 1866(12):118539. PMID: 31491448
Genome integrity is essential for proper cell function such that genetic instability can result in cellular dysfunction and disease. Mutations in the human genome are not random, and occur more...
6.
Del Mundo I, Cho E, Dalby K, Vasquez K
Nucleic Acids Res . 2019 Apr; 47(13):e73. PMID: 30949695
Regions of genomic instability are not random and often co-localize with DNA sequences that can adopt alternative DNA structures (i.e. non-B DNA, such as H-DNA). Non-B DNA-forming sequences are highly...