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Ilya Yakavets

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Articles 28
Citations 291
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Recent Articles
1.
Koca Findik B, Yakavets I, Lassalle H, Catak S, Monari A
J Phys Chem B . 2024 Nov; 128(47):11625-11633. PMID: 39535104
Photodynamic therapy (PDT) represents a most attractive therapeutic strategy to reduce side-effects of chemotherapy and improve the global quality of life of patients. Yet, many PDT drugs suffer from poor...
2.
Kheiri S, Yakavets I, Cruickshank J, Ahmadi F, Berman H, Cescon D, et al.
Adv Mater . 2024 Sep; 36(44):e2410547. PMID: 39276011
Multicellular spheroids and patient-derived organoids find many applications in fundamental research, drug discovery, and regenerative medicine. Advances in the understanding and recapitulation of organ functionality and disease development require the...
3.
Yakavets I, Ayachit M, Kheiri S, Chen Z, Rakhshani F, McWhirter S, et al.
ACS Appl Mater Interfaces . 2024 Feb; 16(8):9690-9701. PMID: 38357740
The development of in vitro models recapitulating nanoparticle transport under physiological flow conditions is of great importance for predicting the efficacy of nanoparticle drug carriers. Liposomes are extensively used for...
4.
Prince E, Morozova S, Chen Z, Adibnia V, Yakavets I, Panyukov S, et al.
Proc Natl Acad Sci U S A . 2023 Dec; 120(51):e2220755120. PMID: 38091296
Fibrous networks formed by biological polymers such as collagen or fibrin exhibit nonlinear mechanical behavior. They undergo strong stiffening in response to weak shear and elongational strains, but soften under...
5.
Francois A, Dirheimer L, Chateau A, Lassalle H, Yakavets I, Bezdetnaya L
Int J Nanomedicine . 2023 Nov; 18:6545-6562. PMID: 37965282
Purpose: The tumor microenvironment (TME) is composed of various stromal components, including immune cells such as tumor-associated macrophages (TAMs), which play a crucial role in cancer initiation and progression. TAMs...
6.
Kheiri S, Chen Z, Yakavets I, Rakhshani F, Young E, Kumacheva E
Biotechnol J . 2023 Jul; 18(10):e2200621. PMID: 37436706
Spheroid-on-a-chip platforms are emerging as promising in vitro models that enable screening of the efficacy of biologically active ingredients. Generally, the supply of liquids to spheroids occurs in the steady...
7.
Lamy L, Francois M, Bezdetnaya L, Yakavets I
Eur J Pharm Biopharm . 2023 Jan; 184:1-6. PMID: 36682510
Photodynamic therapy is a multistage treatment, in which cancerous and precancerous cells are destroyed by light activation of a drug (photosensitizer). For a long time, high cellular uptake of the...
8.
Chen Z, Khuu N, Xu F, Kheiri S, Yakavets I, Rakhshani F, et al.
Gels . 2022 Nov; 8(11). PMID: 36354593
Many fibrous biological tissues exhibit structural anisotropy due to the alignment of fibers in the extracellular matrix. To study the impact of such anisotropy on cell proliferation, orientation, and mobility,...
9.
Navrotskaya A, Aleksandrova D, Chekini M, Yakavets I, Kheiri S, Krivoshapkina E, et al.
ACS Nano . 2022 Apr; 16(6):8641-8650. PMID: 35451833
Food, chemicals, agricultural products, drugs, and vaccines should be transported and stored within an appropriate low-temperature range, following cold chain logistics. Violations of the required temperature regime are generally reported...
10.
Yakavets I, Yankovsky I, Zorina T, Belevtsev M, Bezdetnaya L, Zorin V
Pharmaceutics . 2021 Aug; 13(7). PMID: 34371745
Photodynamic therapy represents a more targeted and less invasive alternative cancer treatment to traditional modalities. Temoporfin, as with many photosensitizers, is given by injection into a vein, and its subsequent...