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Aurelie Francois

Explore the profile of Aurelie Francois including associated specialties, affiliations and a list of published articles. Areas
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Articles 24
Citations 3099
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Recent Articles
1.
Laarif M, Lefevre P, Francois A, Lejeune V, Freymann J, Hennaux V
Ann Biol Clin (Paris) . 2025 Feb; 82(6):618-629. PMID: 39898847
Bacterial vaginosis, one of the most common pathologies in adult women, is defined as a chronic polymicrobial condition resulting from dysbiosis of the vaginal microbiota. Despite 70 % of patients...
2.
Dardare J, Witz A, Betz M, Francois A, Lamy L, Husson M, et al.
Cell Death Discov . 2024 Sep; 10(1):411. PMID: 39333096
Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest cancers. Therapeutic options for PDAC are primarily restricted to surgery in the early stages of the disease or chemotherapy in advanced...
3.
Dirheimer L, Pons T, Francois A, Lamy L, Marchal F, Dolivet G, et al.
Photodiagnosis Photodyn Ther . 2024 Sep; 49:104337. PMID: 39332607
Background: Oral squamous cell carcinoma (OSCC) treatment mainly relies on surgery. The status of surgical margin is a major prognostic factor for patients as positive margins are associated with lower...
4.
Francois A, Dirheimer L, Chateau A, Lassalle H, Yakavets I, Bezdetnaya L
Int J Nanomedicine . 2023 Nov; 18:6545-6562. PMID: 37965282
Purpose: The tumor microenvironment (TME) is composed of various stromal components, including immune cells such as tumor-associated macrophages (TAMs), which play a crucial role in cancer initiation and progression. TAMs...
5.
Witz A, Dardare J, Francois A, Husson M, Rouyer M, Demange J, et al.
Sci Rep . 2023 Nov; 13(1):18741. PMID: 37907567
Pancreatic cancer is one of the most aggressive diseases with a very poor outcome. Olaparib, a PARP inhibitor, as maintenance therapy showed benefits in patients with metastatic pancreatic adenocarcinoma bearing...
6.
Dardare J, Witz A, Betz M, Francois A, Meras M, Lamy L, et al.
Front Oncol . 2022 Dec; 12:1052163. PMID: 36568213
Introduction: Damage specific DNA binding protein 2 (DDB2) is an UV-indiced DNA damage recognition factor and regulator of cancer development and progression. DDB2 has dual roles in several cancers, either...
7.
Siblini Y, Chery C, Rouyer P, Raso J, Julien A, Hergalant S, et al.
Clin Epigenetics . 2021 Dec; 13(1):212. PMID: 34852845
Background: Although radiation therapy represents a core cancer treatment modality, its efficacy is hampered by radioresistance. The effect of ionizing radiations (IRs) is well known regarding their ability to induce...
8.
Egloff-Juras C, Yakavets I, Scherrer V, Francois A, Bezdetnaya L, Lassalle H, et al.
Int J Mol Sci . 2021 Mar; 22(4). PMID: 33671198
Near-infrared (NIR) fluorescence-guided surgery is an innovative technique for the real-time visualization of resection margins. The aim of this study was to develop a head and neck multicellular tumor spheroid...
9.
Yakavets I, Francois A, Lamy L, Piffoux M, Gazeau F, Wilhelm C, et al.
J Nanobiotechnology . 2021 Jan; 19(1):3. PMID: 33407564
Background: Despite the highly expected clinical application of nanoparticles (NPs), the translation of NPs from lab to the clinic has been relatively slow. Co-culture 3D spheroids account for the 3D...
10.
Yakavets I, Francois A, Guiot M, Lequeux N, Fragola A, Pons T, et al.
Cancers (Basel) . 2020 Dec; 12(12). PMID: 33322532
The efficient intraoperative identification of cancers requires the development of the bright, minimally-toxic, tumor-specific near-infrared (NIR) probes as contrast agents. Luminescent semiconductor quantum dots (QDs) offer several unique advantages for...