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Ilona Holcomb

Explore the profile of Ilona Holcomb including associated specialties, affiliations and a list of published articles. Areas
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Articles 9
Citations 124
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Recent Articles
1.
Kapoor S, Sen S, Tsang J, Yap Q, Park S, Cromarty J, et al.
Vet Sci . 2024 Aug; 11(8). PMID: 39195785
Feline lymphoma, a prevalent cancer in cats, exhibits varied prognoses influenced by anatomical site and cellular characteristics. In this study, we investigated the utility of flow cytometry and clonality analysis...
2.
Holcomb I, Bansal N, Duong T, Babb P, Laliberte J, Swaminathan K, et al.
J Biomol Tech . 2022 Jul; 32(4). PMID: 35837268
Single-cell RNA sequencing (scRNA-seq) has the ability to classify each cell and determine the transcriptomic profile of specific cell types and cells of a given disease state; however, sensitivity of...
3.
Gong H, Wang X, Liu B, Boutet S, Holcomb I, Dakshinamoorthy G, et al.
Sci Rep . 2017 Jun; 7(1):2776. PMID: 28584233
We have investigated the correlation between proteins and mRNAs in single cells employing an integrated workflow for dual-analyte co-detection. This is achieved by combining the oligo extension reaction (OER), which...
4.
Ramalingam N, Fowler B, Szpankowski L, Leyrat A, Hukari K, Maung M, et al.
Front Bioeng Biotechnol . 2017 Mar; 5:11. PMID: 28299310
[This corrects the article on p. 70 in vol. 4, PMID: 27709111.].
5.
Ramalingam N, Fowler B, Szpankowski L, Leyrat A, Hukari K, Maung M, et al.
Front Bioeng Biotechnol . 2016 Oct; 4:70. PMID: 27709111
The study of single cells has evolved over the past several years to include expression and genomic analysis of an increasing number of single cells. Several studies have demonstrated wide...
6.
Gong H, Holcomb I, Ooi A, Wang X, Majonis D, Unger M, et al.
Bioconjug Chem . 2015 Dec; 27(1):217-25. PMID: 26689321
The diversity of nucleic acid sequences enables genomics studies in a highly multiplexed format. Since multiplex protein detection is still a challenge, it would be useful to use genomics tools...
7.
Pearlman A, Campbell C, Brooks E, Genshaft A, Shajahan S, Ittman M, et al.
J Probab Stat . 2014 Nov; 2012(2012):873570. PMID: 25419216
The transition of cancer from a localized tumor to a distant metastasis is not well understood for prostate and many other cancers, partly, because of the scarcity of tumor samples,...
8.
Mostaghel E, Geng L, Holcomb I, Coleman I, Lucas J, True L, et al.
Cancer Res . 2010 Feb; 70(4):1286-95. PMID: 20124490
Inhibitors of 5alpha-reductase (SRD5A) that lower intraprostatic levels of dihydrotestosterone (DHT) reduce the overall incidence of prostate cancer (PCa), but there is significant variation in chemopreventive activity between individual men....
9.
Ross S, Spencer S, Holcomb I, Tan C, Hongo J, Devaux B, et al.
Cancer Res . 2002 May; 62(9):2546-53. PMID: 11980648
We conducted an expression analysis of prostate stem cell antigen (PSCA)in normal urogenital tissues, benign prostatic hyperplasia (n = 21), prostatic intraepithelial neoplasia (n = 33), and primary (n =...