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Ilaria Ottonelli

Explore the profile of Ilaria Ottonelli including associated specialties, affiliations and a list of published articles. Areas
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Articles 23
Citations 228
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Recent Articles
1.
Ottonelli I, Baraldi C, Ruozi B, Vandelli M, Tosi G, Duskey J
Nanomedicine (Lond) . 2025 Jan; :1-3. PMID: 39851097
No abstract available.
2.
Cuoghi S, Caraffi R, Anderlini A, Baraldi C, Enzo E, Vandelli M, et al.
Wiley Interdiscip Rev Nanomed Nanobiotechnol . 2024 Jul; 16(4):e1979. PMID: 38955512
Enzyme-based therapy has garnered significant attention for its current applications in various diseases. Despite the notable advantages associated with the use of enzymes as therapeutic agents, that could have high...
3.
Ottonelli I, Adani E, Bighinati A, Cuoghi S, Tosi G, Vandelli M, et al.
Int J Nanomedicine . 2024 May; 19:4235-4251. PMID: 38766661
Purpose: In recent years, microfluidic technologies have become mainstream in producing gene therapy nanomedicines (NMeds) following the Covid-19 vaccine; however, extensive optimizations are needed for each NMed type and genetic...
4.
Rinaldi A, Dumas F, Duskey J, Imbriano C, Belluti S, Roy C, et al.
Int J Pharm . 2024 Mar; 654:123994. PMID: 38484859
Small interfering RNA (siRNA) holds great potential to treat many difficult-to-treat diseases, but its delivery remains the central challenge. This study aimed at investigating the suitability of polymer-lipid hybrid nanomedicines...
5.
Ottonelli I, Sharma A, Ruozi B, Tosi G, Duskey J, Vandelli M, et al.
Adv Neurobiol . 2023 Jul; 32:385-416. PMID: 37480467
Curcumin is a well-known antioxidant used as traditional medicine in China and India since ages to treat variety of inflammatory ailments as a food supplement. Curcumin has antitumor properties with...
6.
Ottonelli I, Duskey J, Genovese F, Pederzoli F, Caraffi R, Valenza M, et al.
Int J Pharm X . 2023 Jul; 5:100182. PMID: 37396626
[This corrects the article DOI: 10.1016/j.ijpx.2022.100136.].
7.
Birolini G, Valenza M, Ottonelli I, Talpo F, Minoli L, Cappelleri A, et al.
Pharmacol Res . 2023 Jun; 194:106823. PMID: 37336430
Evidence that Huntington's disease (HD) is characterized by impaired cholesterol biosynthesis in the brain has led to strategies to increase its level in the brain of the rapidly progressing R6/2...
8.
Moretti M, Caraffi R, Lorenzini L, Ottonelli I, Sannia M, Alastra G, et al.
Cells . 2023 May; 12(9). PMID: 37174731
Spinal cord injury (SCI) is characterized by a cascade of events that lead to sensory and motor disabilities. To date, this condition is irreversible, and no cure exists. To improve...
9.
Roda F, Caraffi R, Picciolini S, Tosi G, Vandelli M, Ruozi B, et al.
Int J Mol Sci . 2023 Feb; 24(3). PMID: 36768820
Glioblastoma multiforme (GBM) is the most common malignant brain tumor, associated with low long-term survival. Nanoparticles (NPs) developed against GBM are a promising strategy to improve current therapies, by enhancing...
10.
Ottonelli I, Bighinati A, Adani E, Loll F, Caraffi R, Vandelli M, et al.
Pharmaceutics . 2023 Jan; 15(1). PMID: 36678654
A drawback in the development of treatments that can reach the retina is the presence of barriers in the eye that restrain compounds from reaching the target. Intravitreal injections hold...