Il-Shin Lee
Overview
Explore the profile of Il-Shin Lee including associated specialties, affiliations and a list of published articles.
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Articles
12
Citations
345
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Recent Articles
1.
Shin J, Jung K, Kim M, Hwang K, Lee H, Kim I, et al.
Exp Mol Med
. 2018 Apr;
50(4):1-18.
PMID: 29674624
Hypoxic-ischemic (HI) brain injury and spinal cord injury (SCI) lead to extensive tissue loss and axonal degeneration. The combined application of the polymer scaffold and neural progenitor cells (NPCs) has...
2.
Kim M, Jung K, Kim I, Lee I, Ko Y, Shin J, et al.
Exp Mol Med
. 2018 Apr;
50(4):1-14.
PMID: 29622770
Neural progenitor cell (NPC) transplantation has been shown to be beneficial in the ischemic brain. However, the low survival rate of transplanted NPCs in an ischemic microenvironment limits their therapeutic...
3.
Yun S, Shin T, Lee J, Cho M, Kim I, Kim J, et al.
Nano Lett
. 2018 Feb;
18(2):838-845.
PMID: 29393650
Cell-based therapies are attractive for treating various degenerative disorders and cancer but delivering functional cells to the region of interest in vivo remains difficult. The problem is exacerbated in dense...
4.
Lee I, Koo K, Jung K, Kim M, Kim I, Hwang K, et al.
Transl Res
. 2017 Jan;
183:121-136.e9.
PMID: 28081931
Neonatal hypoxic-ischemic (HI) brain injury leads to high mortality and neurodevelopmental disabilities. Multipotent neural progenitor cells (NPCs) with self-renewing capacity have the potential to reduce neuronal loss and improve the...
5.
Shin J, Kim K, Yoo J, Kim I, Yun S, Lee H, et al.
Neural Plast
. 2015 Nov;
2015:630932.
PMID: 26568892
In a phase I/IIa open-label and nonrandomized controlled clinical trial, we sought to assess the safety and neurological effects of human neural stem/progenitor cells (hNSPCs) transplanted into the injured cord...
6.
Lee I, Jung K, Kim I, Lee H, Kim M, Yun S, et al.
Mol Neurodegener
. 2015 Aug;
10:38.
PMID: 26293123
Background: Alzheimer's disease (AD) is an inexorable neurodegenerative disease that commonly occurs in the elderly. The cognitive impairment caused by AD is associated with abnormal accumulation of amyloid-β (Aβ) and...
7.
Lee H, Yun S, Kim I, Lee I, Shin J, Park S, et al.
PLoS One
. 2014 Aug;
9(8):e104092.
PMID: 25105891
Cell transplantation has been suggested as an alternative therapy for temporal lobe epilepsy (TLE) because this can suppress spontaneous recurrent seizures in animal models. To evaluate the therapeutic potential of...
8.
Lee I, Jung K, Kim I, Park K
Exp Mol Med
. 2013 Nov;
45:e60.
PMID: 24232259
Alzheimer's disease (AD) is the most common cause of age-related dementia. The neuropathological hallmarks of AD include extracellular deposition of amyloid-β peptides and neurofibrillary tangles that lead to intracellular hyperphosphorylated...
9.
Lee I, Jung K, Kim M, Park K
Pediatr Int
. 2010 Oct;
52(6):855-65.
PMID: 21029253
Neural stem cells (NSCs) are defined by their ability to self-renew, to differentiate into cells of all glial and neuronal lineages throughout the neuraxis, and to populate developing or degenerating...
10.
Park S, Kim H, Yun S, Kim I, Lee J, Lee I, et al.
Exp Mol Med
. 2009 Mar;
41(7):487-500.
PMID: 19322031
Neural progenitor cells (NPs) have shown several promising benefits for the treatment of neurological disorders. To evaluate the therapeutic potential of human neural progenitor cells (hNPs) in amyotrophic lateral sclerosis...