Ikuo Kimura
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Explore the profile of Ikuo Kimura including associated specialties, affiliations and a list of published articles.
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105
Citations
4627
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Recent Articles
11.
Uehira Y, Ueno H, Miyamoto J, Kimura I, Ishizawa Y, Iijima H, et al.
Obes Res Clin Pract
. 2023 Sep;
17(5):411-420.
PMID: 37679239
Orlistat, an anti-obesity agent, inhibits the metabolism and absorption of dietary fat by inactivating pancreatic lipase in the gut. The effect of orlistat on the gut microbiota of Japanese individuals...
12.
Sato K, Ohno-Oishi M, Yoshida M, Sato T, Aizawa T, Sasaki Y, et al.
Glia
. 2023 Jul;
71(11):2609-2622.
PMID: 37470163
Resident microglia are important to maintain homeostasis in the central nervous system, which includes the retina. The retinal microglia become activated in numerous pathological conditions, but the molecular signatures of...
13.
Nagai M, Moriyama M, Ishii C, Mori H, Watanabe H, Nakahara T, et al.
Nat Commun
. 2023 Jun;
14(1):3863.
PMID: 37391427
Fever is a common symptom of influenza and coronavirus disease 2019 (COVID-19), yet its physiological role in host resistance to viral infection remains less clear. Here, we demonstrate that exposure...
14.
Ito T, Nakanishi Y, Shibata R, Sato N, Jinnohara T, Suzuki S, et al.
Gut Microbes
. 2023 May;
15(1):2206507.
PMID: 37131293
Evidence has accumulated that gut microbiota and its metabolites, in particular the short-chain fatty acid propionate, are significant contributors to the pathogenesis of a variety of diseases. However, little is...
15.
Katoh T, Yamada C, Wallace M, Yoshida A, Gotoh A, Arai M, et al.
Nat Chem Biol
. 2023 Mar;
19(6):778-789.
PMID: 36864192
Mucinolytic bacteria modulate host-microbiota symbiosis and dysbiosis through their ability to degrade mucin O-glycans. However, how and to what extent bacterial enzymes are involved in the breakdown process remains poorly...
16.
Igarashi M, Iwasa K, Hayakawa T, Tsuduki T, Kimura I, Maruyama K, et al.
Front Endocrinol (Lausanne)
. 2023 Feb;
13:1056116.
PMID: 36733808
Introduction: Among the fatty acid ethanolamides (FAEs), oleoylethanolamide (OEA), linoleoylethanolamide (LEA), and palmitoylethanolamide (PEA) are reported to be involved in feeding regulation. In particular, OEA is well characterized as a...
17.
Miyamoto J, Shimizu H, Hisa K, Matsuzaki C, Inuki S, Ando Y, et al.
Gut Microbes
. 2023 Jan;
15(1):2161271.
PMID: 36604628
Fermented foods demonstrate remarkable health benefits owing to probiotic bacteria or microproducts produced via bacterial fermentation. Fermented foods are produced by the fermentative action of several lactic acid bacteria, including...
18.
Ohue-Kitano R, Nonaka H, Nishida A, Masujima Y, Takahashi D, Ikeda T, et al.
JCI Insight
. 2022 Dec;
8(2).
PMID: 36480287
Medium-chain triglycerides (MCTs), which consist of medium-chain fatty acids (MCFAs), are unique forms of dietary fat with various health benefits. G protein-coupled 84 (GPR84) acts as a receptor for MCFAs...
19.
Igarashi M, Hayakawa T, Tanabe H, Watanabe K, Nishida A, Kimura I
Mol Metab
. 2022 Dec;
67:101649.
PMID: 36462626
Objective: The gastrointestinal tract affects physiological activities and behavior by secreting hormones and generating signals through the activation of nutrient sensors. GPR119, a lipid sensor, is indirectly involved in the...
20.
Mio K, Iida-Tanaka N, Yamanaka C, Kimura I, Aoe S
Food Funct
. 2022 Oct;
13(21):10970-10980.
PMID: 36254783
Barley consumption is expected to increase insulin sensitivity by increasing the level of short-chain fatty acids (SCFAs) and promoting the secretion of GLP-1. However, the involvement of GPR43, a receptor...