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Ikuko Yokota

Explore the profile of Ikuko Yokota including associated specialties, affiliations and a list of published articles. Areas
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Articles 23
Citations 102
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Recent Articles
11.
Miura N, Hanamatsu H, Yokota I, Okada K, Furukawa J, Shinohara Y
Biomolecules . 2020 Oct; 10(10). PMID: 32998456
Glycans present extraordinary structural diversity commensurate with their involvement in numerous fundamental cellular processes including growth, differentiation, and morphogenesis. Unlike linear DNA and protein sequences, glycans have heterogeneous structures that...
12.
Sunami H, Shimizu Y, Denda J, Yokota I, Kishimoto H, Igarashi Y
Adv Biosyst . 2020 Sep; 4(10):e2000113. PMID: 32924291
The present study demonstrates unidirectional cell migration using a novel 3D microfabricated scaffold, as revealed by the uneven sorting of cells into an area of 1 mm × 1 mm....
13.
Furukawa J, Hanamatsu H, Nishikaze T, Manya H, Miura N, Yagi H, et al.
Anal Chem . 2020 Sep; 92(21):14383-14392. PMID: 32881480
Sialic acid attached to nonreducing ends of glycan chains via different linkages is associated with specific interactions and physiological events. Linkage-specific derivatization of sialic acid is of great interest for...
14.
Sunami H, Yokota I, Igarashi Y
Biomater Sci . 2020 Jun; 2(3):399-409. PMID: 32481866
To determine how the three-dimensional (3D) shape of scaffolds influences cell functions, 3D micropatterned scaffolds of various sizes were fabricated on a silicon substrate. The micropatterns were equilateral triangular pores...
15.
Hanamatsu H, Nishikaze T, Tsumoto H, Ogawa K, Kobayashi T, Yokota I, et al.
Anal Chem . 2019 Oct; 91(21):13343-13348. PMID: 31577134
Sialic acids form the terminal sugars in glycan chains on glycoproteins via α2,3, α2,6, or α2,8 linkages, and structural isomers of sialyl linkages play various functional roles in cell recognition...
16.
Homan K, Hanamatsu H, Furukawa J, Okada K, Yokota I, Onodera T, et al.
Int J Mol Sci . 2019 Jul; 20(14). PMID: 31331074
In normal articular cartilage, chondrocytes do not readily proliferate or terminally differentiate, and exhibit a low level of metabolism. Hypertrophy-like changes of chondrocytes have been proposed to play a role...
17.
Oki N, Sayama T, Ishimoto M, Yokota I, Kaga A, Takahashi M, et al.
Breed Sci . 2019 Jan; 68(5):554-560. PMID: 30697116
Manipulating the genetic control of plant height is essential in soybean breeding to increase yield through the enlargement of the plant size while preventing lodging. A Japanese soybean germplasm, Y2,...
18.
Furukawa J, Soga M, Okada K, Yokota I, Piao J, Irie T, et al.
J Proteome Res . 2017 Jun; 16(8):2802-2810. PMID: 28628327
Niemann-Pick disease type C (NPC) is an autosomal recessive lipid storage disorder, and the majority of cases are caused by mutations in the NPC1 gene. In this study, we clarified...
19.
Sunami H, Shimizu Y, Denda J, Yokota I, Yoshizawa T, Uechi Y, et al.
J Biomed Mater Res B Appl Biomater . 2017 May; 106(3):976-985. PMID: 28474403
Here, a new technology was developed to selectively produce areas of high and low surface Young's modulus on biomedical polymer films using micropatterns. First, an elastic polymer film was adhered...
20.
Furukawa J, Sakai S, Yokota I, Okada K, Hanamatsu H, Kobayashi T, et al.
J Lipid Res . 2015 Oct; 56(12):2399-407. PMID: 26420879
Glycosphingolipids (GSLs) are lipid molecules linked to carbohydrate units that form the plasma membrane lipid raft, which is clustered with sphingolipids, sterols, and specific proteins, and thereby contributes to membrane...