Ikuko Hosokawa
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Explore the profile of Ikuko Hosokawa including associated specialties, affiliations and a list of published articles.
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40
Citations
251
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Recent Articles
1.
Okamoto R, Hosokawa Y, Hosokawa I, Ozaki K, Hosaka K
Immunopharmacol Immunotoxicol
. 2025 Jan;
:1-6.
PMID: 39748667
Objectives: Periodontal disease is a chronic inflammatory disease caused by periodontopathogenic bacteria, and its progression leads to periodontal tissue destruction and tooth loss. Zerumbone is a bioactive substance found in...
2.
Mieda K, Nakanishi T, Kuramoto H, Hosokawa Y, Hosokawa I, Takegawa D, et al.
Cell Biochem Biophys
. 2024 Dec;
PMID: 39739289
Sudachitin, which is a polymethoxy flavonoid derived from the peer of Citrus sudachi, has several biological properties. However, the effect of sudachitin on human dental pulp cells (HDPCs) remains unclear....
3.
Okamoto R, Hosokawa Y, Hosokawa I, Ozaki K, Hosaka K
Immunopharmacol Immunotoxicol
. 2024 Jun;
46(4):521-528.
PMID: 38918176
Objective: Periodontis is a chronic inflammatory disease induced by periodontopathogenic bacteria. The excessive immune response caused by persistent bacterial infection leads to alveolar bone resorption and ultimately tooth loss. Cardamonin...
4.
Okamoto R, Hosokawa Y, Hosokawa I, Ozaki K, Hosaka K
Mol Biol Rep
. 2024 Jan;
51(1):222.
PMID: 38281189
Background: Cardamonin is classified as a natural chalcone, and has been reported to possess various bioactive effects. However, there have been limited attempts to utilize cardamonin in the treatment of...
5.
Hosokawa Y, Hosokawa I, Shimoyama M, Okamoto R, Ozaki K, Hosaka K
Naunyn Schmiedebergs Arch Pharmacol
. 2023 Oct;
397(4):2233-2240.
PMID: 37804343
Berteroin is a bioactive substance classified as an isothiocyanate found in cruciferous vegetables such as cabbage, arugula, and salad leaves. In this study, we aimed to determine whether berteroin exerts...
6.
Shimoyama M, Hosokawa Y, Hosokawa I, Ozaki K, Hosaka K
Immunopharmacol Immunotoxicol
. 2023 Aug;
46(1):49-54.
PMID: 37624680
Objectives: Periodontitis is a chronic inflammatory disease induced by periodontal disease-causing bacteria. It has been shown that excessive immune response against bacteria is involved in periodontal tissue destruction including alveolar...
7.
Hosokawa Y, Hosokawa I, Shimoyama M, Fujii A, Sato J, Kadena K, et al.
Biomedicines
. 2022 Dec;
10(12).
PMID: 36551911
Iberin is a bioactive chemical found in cruciferous plants that has been demonstrated to have anticancer properties. However, there have been no reports on its effects on periodontal resident cells,...
8.
Shimoyama M, Hosokawa Y, Hosokawa I, Ozaki K, Hosaka K
Curr Issues Mol Biol
. 2022 Jul;
44(7):2915-2922.
PMID: 35877425
6-(Methylsulfinyl) hexyl isothiocyanate (6-MSITC) is a bioactive substance found in wasabi (Wasabia japonica) and has been reported to have some bioactive effects including anticancer and antioxidant effects. However, there are...
9.
Hosokawa Y, Hosokawa I, Ozaki K
Mediators Inflamm
. 2021 Aug;
2021:5535844.
PMID: 34335088
Nobiletin, a biologically active substance in the skin of citrus fruits, has been reported to be an effective anti-inflammatory, anticancer, and antimicrobial agent. In this study, we aimed to examine...
10.
Hosokawa Y, Hosokawa I, Ozaki K, Matsuo T
Pharmaceutics
. 2021 Jun;
13(5).
PMID: 34066937
The immune response in periodontal lesions is involved in the progression of periodontal disease. Therefore, it is important to find a bioactive substance that has anti-inflammatory effects in periodontal lesions....