Ihsen Youssef
Overview
Explore the profile of Ihsen Youssef including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
15
Citations
574
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Carvalho K, Martin E, Ces A, Sarrazin N, Lagouge-Roussey P, Nous C, et al.
Prog Neurobiol
. 2021 Aug;
206:102139.
PMID: 34391810
Alzheimer's disease is the most common form of dementia characterized by intracellular aggregates of hyperphosphorylated Tau protein and extracellular accumulation of amyloid β (Aβ) peptides. We previously demonstrated that the...
2.
Li T, Martin E, Abada Y, Boucher C, Ces A, Youssef I, et al.
J Alzheimers Dis
. 2020 Jul;
76(4):1339-1345.
PMID: 32623401
Background: Masitinib is a selective tyrosine kinase inhibitor that modulates mast cells activity. A previous phase II study reported a cognitive effect of masitinib in patients with Alzheimer's disease. Objective:...
3.
Su M, Naderi K, Samson N, Youssef I, Fulop L, Bozso Z, et al.
Mol Neurobiol
. 2019 Jan;
56(8):5815-5834.
PMID: 30684218
Current evidence suggests dementia and pathology in Alzheimer's Disease (AD) are both dependent and independent of amyloid processing and can be induced by multiple 'hits' on vital neuronal functions. Type...
4.
Martin E, Amar M, Dalle C, Youssef I, Boucher C, Le Duigou C, et al.
Mol Psychiatry
. 2018 Jun;
24(1):108-125.
PMID: 29934546
Extracellular aggregates of amyloid β (Aβ) peptides, which are characteristic of Alzheimer's disease (AD), act as an essential trigger for glial cell activation and the release of ATP, leading to...
5.
Androuin A, Potier B, Nagerl U, Cattaert D, Danglot L, Thierry M, et al.
Acta Neuropathol
. 2018 Apr;
135(6):839-854.
PMID: 29696365
Alzheimer's disease (AD) is associated with a progressive loss of synapses and neurons. Studies in animal models indicate that morphological alterations of dendritic spines precede synapse loss, increasing the proportion...
6.
Li T, Vandesquille M, Koukouli F, Dudeffant C, Youssef I, Lenormand P, et al.
J Control Release
. 2016 Nov;
243:1-10.
PMID: 27671875
Detection of intracerebral targets with imaging probes is challenging due to the non-permissive nature of blood-brain barrier (BBB). The present work describes two novel single-domain antibodies (VHHs or nanobodies) that...
7.
Epelbaum S, Youssef I, Lacor P, Chaurand P, Duplus E, Brugg B, et al.
Neurobiol Aging
. 2015 Apr;
36(6):2043-52.
PMID: 25862419
Amyloid-β (Aβ) oligomers are the suspected culprit as initiators of Alzheimer's disease (AD). However, their diffusion in the brain remains unknown. Here, we studied Aβ oligomers' dissemination and evaluated their...
8.
Ando K, Laborde Q, Lazar A, Godefroy D, Youssef I, Amar M, et al.
Acta Neuropathol
. 2014 Jul;
128(3):457-9.
PMID: 25069432
No abstract available.
9.
Lazar A, Mourtas S, Youssef I, Parizot C, Dauphin A, Delatour B, et al.
Nanomedicine
. 2012 Dec;
9(5):712-21.
PMID: 23220328
From The Clinical Editor: In this preclinical study, curcumin-conjugated nanoliposomes were investigated as possible diagnostics and targeted drug delivery system in Alzheimer's disease, demonstrating strong labeling of Aβ deposits both...
10.
Desbene C, Malaplate-Armand C, Youssef I, Garcia P, Stenger C, Sauvee M, et al.
Neurobiol Aging
. 2011 Dec;
33(6):1123.e17-29.
PMID: 22188721
Soluble beta-amyloid (Aβ) oligomers are considered to putatively play a critical role in the early synapse loss and cognitive impairment observed in Alzheimer's disease. We previously demonstrated that Aβ oligomers...