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Igor Tolstoy

Explore the profile of Igor Tolstoy including associated specialties, affiliations and a list of published articles. Areas
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Articles 18
Citations 4654
Followers 0
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Recent Articles
1.
Joos R, Boucher K, Lavelle A, Arumugam M, Blaser M, Claesson M, et al.
Nat Rev Microbiol . 2024 Dec; 23(3):206. PMID: 39681696
No abstract available.
2.
Joos R, Boucher K, Lavelle A, Arumugam M, Blaser M, Claesson M, et al.
Nat Rev Microbiol . 2024 Oct; 23(3):192-205. PMID: 39443812
Human microbiomes are essential to health throughout the lifespan and are increasingly recognized and studied for their roles in metabolic, immunological and neurological processes. Although the full complexity of these...
3.
Yutin N, Tolstoy I, Mutz P, Wolf Y, Krupovic M, Koonin E
Virol J . 2024 Aug; 21(1):200. PMID: 39187833
Background: Viruses with double-stranded (ds) DNA genomes in the realm Duplodnaviria share a conserved structural gene module but show a broad range of variation in their repertoires of DNA replication...
4.
Yutin N, Tolstoy I, Mutz P, Wolf Y, Krupovic M, Koonin E
bioRxiv . 2024 Jun; PMID: 38903090
Viruses with double-stranded (ds) DNA genomes in the realm share a conserved structural gene module but show a broad range of variation in their repertoires of DNA replication proteins. Some...
5.
Hehnly C, Shi A, Ssentongo P, Zhang L, Isaacs A, Morton S, et al.
mBio . 2022 Nov; 13(6):e0268822. PMID: 36374038
Hydrocephalus, the leading indication for childhood neurosurgery worldwide, is particularly prevalent in low- and middle-income countries. Hydrocephalus preceded by an infection, or postinfectious hydrocephalus, accounts for up to 60% of...
6.
Turner D, Adriaenssens E, Tolstoy I, Kropinski A
Phage (New Rochelle) . 2022 Jan; 2(4):170-182. PMID: 35083439
All sequencing projects of bacteriophages (phages) should seek to report an accurate and comprehensive annotation of their genomes. This article defines 14 questions for those new to phage genomics that...
7.
Moya-Beltran A, Makarova K, Acuna L, Wolf Y, Covarrubias P, Shmakov S, et al.
CRISPR J . 2021 Sep; 4(5):656-672. PMID: 34582696
Type IV CRISPR-Cas are a distinct variety of highly derived CRISPR-Cas systems that appear to have evolved from type III systems through the loss of the target-cleaving nuclease and partial...
8.
Yutin N, Benler S, Shmakov S, Wolf Y, Tolstoy I, Rayko M, et al.
Nat Commun . 2021 Feb; 12(1):1044. PMID: 33594055
CrAssphage is the most abundant human-associated virus and the founding member of a large group of bacteriophages, discovered in animal-associated and environmental metagenomes, that infect bacteria of the phylum Bacteroidetes....
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Feldgarden M, Brover V, Haft D, Prasad A, Slotta D, Tolstoy I, et al.
Antimicrob Agents Chemother . 2019 Aug; 63(11). PMID: 31427293
Antimicrobial resistance (AMR) is a major public health problem that requires publicly available tools for rapid analysis. To identify AMR genes in whole-genome sequences, the National Center for Biotechnology Information...