Igor Prudovsky
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Explore the profile of Igor Prudovsky including associated specialties, affiliations and a list of published articles.
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Articles
71
Citations
1344
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Recent Articles
1.
Siviski M, Bercovitch R, Pyburn K, Potts C, Pande S, Gartner C, et al.
Int J Mol Sci
. 2025 Mar;
26(5).
PMID: 40076432
Adipogenesis is regulated by the coordinated activity of adipogenic transcription factors including PPAR-gamma and C/EBP alpha, while dysregulated adipogenesis can predispose adipose tissues to adipocyte hypertrophy and hyperplasia. We have...
2.
Prudovsky I, Kacer D, Lindner V, Rappold J, Carter D
Burns
. 2024 Feb;
50(4):947-956.
PMID: 38336496
Burn wound conversion is the observed process where superficial partial thickness burns convert into deep partial or full thickness burn injuries. This conversion process often involves surgical excision to achieve...
3.
Pande S, Vary C, Yang X, Liaw L, Gower L, Friesel R, et al.
Biochem Biophys Res Commun
. 2024 Feb;
701:149552.
PMID: 38335918
The Interleukin-17 (IL17) family is a group of cytokines implicated in the etiology of several inflammatory diseases. Interleukin-17 receptor D (IL17RD), also known as Sef (similar expression to fibroblast growth...
4.
Toomey B, Mitrovic S, Lindner-Liaw M, Leon Vazquez R, Kacer D, Ryzhov S, et al.
Vascul Pharmacol
. 2023 Dec;
153:107246.
PMID: 38040222
CTHRC1 is transiently expressed by activated fibroblasts during tissue repair and in certain cancers, and CTHRC1 derived from osteocytes is detectable in circulation. Because its biological activity is poorly understood,...
5.
Kacer D, Machnitzky E, Fung A, Greene A, Carter D, Rappold J, et al.
Transfusion
. 2023 Apr;
63 Suppl 3:S168-S176.
PMID: 37070378
Introduction: Tranexamic acid (TXA) is widely used as an antifibrinolytic agent in hemorrhagic trauma patients. The beneficial effects of TXA exceed the suppression of blood loss and include the ability...
6.
Prudovsky I, Kacer D, Zucco V, Palmeri M, Falank C, Kramer R, et al.
Transfusion
. 2022 Jul;
62 Suppl 1:S301-S312.
PMID: 35834488
Tranexamic acid (TXA) is a popular antifibrinolytic drug widely used in hemorrhagic trauma patients and cardiovascular, orthopedic, and gynecological surgical patients. TXA binds plasminogen and prevents its maturation to the...
7.
Prudovsky I
Cells
. 2021 Aug;
10(7).
PMID: 34360000
Growth factors belonging to the FGF family play important roles in tissue and organ repair after trauma. In this review, I discuss the regulation by FGFs of the aspects of...
8.
Yin H, Favreau-Lessard A, deKay J, Herrmann Y, Robich M, Koza R, et al.
J Mol Cell Cardiol
. 2020 Dec;
152:1-16.
PMID: 33259856
Background: Myeloid cells play an important role in a wide variety of cardiovascular disorders, including both ischemic and non-ischemic cardiomyopathies. Neuregulin-1 (NRG-1)/ErbB signaling has recently emerged as an important factor...
9.
Ruiz-Villalba A, Romero J, Hernandez S, Vilas-Zornoza A, Fortelny N, Castro-Labrador L, et al.
Circulation
. 2020 Sep;
142(19):1831-1847.
PMID: 32972203
Background: Cardiac fibroblasts (CFs) have a central role in the ventricular remodeling process associated with different types of fibrosis. Recent studies have shown that fibroblasts do not respond homogeneously to...
10.
Robich M, Ryzhov S, Kacer D, Palmeri M, Peterson S, Quinn R, et al.
J Surg Res
. 2020 Mar;
251:287-295.
PMID: 32199337
Background: The endothelial glycocalyx (EG) is involved in critical regulatory mechanisms that maintain endothelial vascular integrity. We hypothesized that prolonged cardiopulmonary bypass (CPB) may be associated with EG degradation. We...