Ignacio Rego-Perez
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Explore the profile of Ignacio Rego-Perez including associated specialties, affiliations and a list of published articles.
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48
Citations
596
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Recent Articles
1.
Duran-Sotuela A, Vazquez-Garcia J, Relano-Fernandez S, Balboa-Barreiro V, Fernandez-Tajes J, Blanco F, et al.
Front Pharmacol
. 2024 Sep;
15:1426826.
PMID: 39346556
Background: In the context of the cytokine storm the takes place in severe COVID-19 patients, the () pathway emerges as one of the key pathways involved in the pathogenesis of...
2.
Dalmao-Fernandez A, Hermida-Gomez T, Nogueira-Recalde U, Rego-Perez I, Blanco-Garcia F, Fernandez-Moreno M
Cells
. 2024 Jun;
13(11.
PMID: 38891108
Authors have demonstrated that apoptosis activation is a pathway related to cartilage degradation characteristics of the OA process. Autophagy is an adaptive response to protect cells from various environmental changes,...
3.
Silva-Diaz M, Pertega-Diaz S, Balboa-Barreiro V, Tilve-Alvarez C, Raga-Sivira A, Rego-Perez I, et al.
Sci Rep
. 2024 Mar;
14(1):5968.
PMID: 38472231
To delineate the phenotype of erosive hand osteoarthritis (EHOA) in a Spanish population and assess its correlation with metabolic syndrome. We conducted a cross-sectional study using baseline data from the...
4.
Duran-Sotuela A, Oreiro N, Fernandez-Moreno M, Vazquez-Garcia J, Relano-Fernandez S, Balboa-Barreiro V, et al.
Osteoarthritis Cartilage
. 2024 Jan;
32(5):526-534.
PMID: 38190960
Objective: To investigate genetic interactions between mitochondrial deoxyribonucleic acid (mtDNA) haplogroups and nuclear single nucleotide polymorphisms (nSNPs) to analyze their impact on the development of the rapid progression of knee...
5.
Duran-Sotuela A, Fernandez-Moreno M, Suarez-Ulloa V, Vazquez-Garcia J, Relano S, Hermida-Gomez T, et al.
Ann Rheum Dis
. 2023 Apr;
82(7):974-984.
PMID: 37024296
Objectives: To identify mitochondrial DNA (mtDNA) genetic variants associated with the risk of rapid progression of knee osteoarthritis (OA) and to characterise their functional significance using a cellular model of...
6.
Styrkarsdottir U, Stefansdottir L, Thorleifsson G, Stefansson O, Saevarsdottir S, Lund S, et al.
Ann Rheum Dis
. 2023 Mar;
82(6):873-880.
PMID: 36931692
Objectives: Erosive hand osteoarthritis (EHOA) is a severe subset of hand osteoarthritis (OA). It is unclear if EHOA is genetically different from other forms of OA. Sequence variants at ten...
7.
Bonakdari H, Pelletier J, Blanco F, Rego-Perez I, Duran-Sotuela A, Aitken D, et al.
BMC Med
. 2022 Sep;
20(1):316.
PMID: 36089590
Background: Knee osteoarthritis is the most prevalent chronic musculoskeletal debilitating disease. Current treatments are only symptomatic, and to improve this, we need a robust prediction model to stratify patients at...
8.
Scotece M, Vaamonde-Garcia C, Lechuga-Vieco A, Cortes A, Gomez M, Filgueira-Fernandez P, et al.
Aging (Albany NY)
. 2022 Jul;
14(15):5966-5983.
PMID: 35779570
Mitochondria and mtDNA variations contribute to specific aspects of the aging process. Here, we aimed to investigate the influence of mtDNA variation on joint damage in a model of aging...
9.
Ramos-Louro P, Arellano Perez Vertti R, Reyes A, Martinez-Nava G, Espinosa R, Pineda C, et al.
Sci Rep
. 2022 Mar;
12(1):5173.
PMID: 35338224
To evaluate the influence of mitochondrial DNA haplogroups on the risk of knee OA in terms of their interaction with obesity, in a population from Mexico. Samples were obtained from...
10.
Oreiro-Villar N, Raga A, Rego-Perez I, Pertega S, Silva-Diaz M, Freire M, et al.
Reumatol Clin (Engl Ed)
. 2022 Feb;
18(2):100-104.
PMID: 35153032
Introduction And Objective: The use of well characterized osteoarthritis (OA) cohorts is mandatory for the study and knowledge of this disease. Currently, there is no prospective cohort in this pathology...