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Ian S Brown

Explore the profile of Ian S Brown including associated specialties, affiliations and a list of published articles. Areas
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Articles 48
Citations 576
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Recent Articles
1.
Serrano J, Kondo S, Link G, Brown I, Pratley R, Baskin K, et al.
Metabolism . 2024 Oct; 162:156045. PMID: 39393515
Background: The TAS1R2 receptor, known for its role in taste perception, has also emerged as a key regulator of muscle physiology. Previous studies have shown that genetic ablation of TAS1R2...
2.
Coady L, Sheahan K, Brown I, Carneiro F, Gill A, Kumarasinghe P, et al.
Expert Rev Gastroenterol Hepatol . 2024 Sep; 18(9):529-539. PMID: 39268773
Introduction: Lymphocyte-rich inflammation of the esophageal mucosa has gained increased awareness among pathologists and clinicians recently. Patients usually present with symptoms of esophageal dysfunction, including dysphagia and food bolus impaction....
3.
Miller G, Sokolova A, Bettington M, Rosty C, Brown I
Pathology . 2024 Jul; 56(6):795-803. PMID: 39025725
The colon is the most common site for endometriosis outside the genital tract. It has a varied presentation and can mimic numerous other conditions, both clinically and pathologically. We investigated...
4.
Serrano J, Boyd J, Brown I, Mason C, Smith K, Karolyi K, et al.
Nat Commun . 2024 Jun; 15(1):4915. PMID: 38851747
The bioavailability of nicotinamide adenine dinucleotide (NAD) is vital for skeletal muscle health, yet the mechanisms or signals regulating NAD homeostasis remain unclear. Here, we uncover a pathway connecting peripheral...
5.
de Lima P, Broit N, Huang J, Lim J, Gardiner D, Brown I, et al.
Front Oncol . 2023 Sep; 13:1231104. PMID: 37746297
Introduction: Cutaneous squamous cell carcinoma of the head and neck (cSCCHN) can metastasize by invading nerves and spread toward the central nervous system. This metastatic process is called perineural invasion...
6.
Serrano J, Boyd J, Mason C, Smith K, Karolyi K, Kondo S, et al.
Res Sq . 2023 Feb; PMID: 36798161
Muscle fitness and mass deteriorate under the conditions of obesity and aging for reasons yet to be fully elucidated. Herein, we describe a novel pathway linking peripheral nutrient sensing and...
7.
Flanagan A, Allsopp S, OConnor S, Tobin J, Pretorius C, Brown I, et al.
Intern Med J . 2022 Dec; 53(9):1602-1609. PMID: 36579712
Background And Aims: To determine the incidence of inflammatory bowel disease (IBD) in the Mackay-Isaac-Whitsunday region in Northern Queensland (-21.14° S) and to allow a comparison with Southern Australian and...
8.
Brown I, Sokolova A, Rosty C, Graham R
Histopathology . 2022 Aug; 82(2):232-241. PMID: 35962741
Cysts of the retrorectal space comprise a heterogeneous group of rare lesions. Most develop from embryological remnants and include tailgut cysts, dermoid cysts, rectal duplication cysts, anal canal duplication cysts,...
9.
Serrano J, Meshram N, Soundarapandian M, Smith K, Mason C, Brown I, et al.
Biomedicines . 2022 Jan; 10(1). PMID: 35052799
Background: Saccharin is a common artificial sweetener and a bona fide ligand for sweet taste receptors (STR). STR can regulate insulin secretion in beta cells, so we investigated whether saccharin...
10.
Brown I, Liu C, Miller G
Adv Anat Pathol . 2021 Dec; 29(1):25-36. PMID: 34879036
Pathologists have an important and expanding role in the diagnosis and management of inflammatory bowel disease. This role includes the initial diagnosis of the disease, assessment of the response to...