Ian Rees
Overview
Explore the profile of Ian Rees including associated specialties, affiliations and a list of published articles.
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Articles
8
Citations
2165
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0
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Recent Articles
1.
Stacey G, Andrews P, Asante C, Barbaric I, Barry J, Bisset L, et al.
Regen Med
. 2018 Nov;
13(8):935-944.
PMID: 30488776
Human pluripotent stem cells (hPSCs) have the potential to transform medicine. However, hurdles remain to ensure safety for such cellular products. Science-based understanding of the requirements for source materials is...
2.
Rees I, Langley E, Chiu W, Ludtke S
Microsc Microanal
. 2013 Jan;
19(1):1-10.
PMID: 23360752
Transmission electron microscopy and associated methods, such as single particle analysis, two-dimensional crystallography, helical reconstruction, and tomography, are highly data-intensive experimental sciences, which also have substantial variability in experimental technique....
3.
Pembroke T, Rees I, Gallagher K, Jones E, Mizen P, Navruzov T, et al.
Eur J Immunol
. 2012 Jun;
42(9):2383-94.
PMID: 22653709
The ability to control HCV with IFN-α-based treatments provides an opportunity in humans to study how the rate of viral clearance in vivo impinges on the development of antiviral responses....
4.
Baker M, Rees I, Ludtke S, Chiu W, Baker M
Structure
. 2012 Mar;
20(3):450-63.
PMID: 22405004
A significant number of macromolecular structures solved by electron cryo-microscopy and X-ray crystallography obtain resolutions of 3.5-6Å, at which direct atomistic interpretation is difficult. To address this, we developed pathwalking,...
5.
Fogg J, Kolmakova N, Rees I, Magonov S, Hansma H, Perona J, et al.
J Phys Condens Matter
. 2011 Sep;
18(14):S145-S159.
PMID: 19337583
Using λ-Int recombination in E. coli, we have generated milligram quantities of supercoiled minicircle DNA. Intramolecular Int recombination was efficient down to lengths ~254 bp. When nicked and religated in...
6.
Lawson C, Baker M, Best C, Bi C, Dougherty M, Feng P, et al.
Nucleic Acids Res
. 2010 Oct;
39(Database issue):D456-64.
PMID: 20935055
Cryo-electron microscopy reconstruction methods are uniquely able to reveal structures of many important macromolecules and macromolecular complexes. EMDataBank.org, a joint effort of the Protein Data Bank in Europe (PDBe), the...
7.
Tang G, Peng L, Baldwin P, Mann D, Jiang W, Rees I, et al.
J Struct Biol
. 2006 Jul;
157(1):38-46.
PMID: 16859925
EMAN is a scientific image processing package with a particular focus on single particle reconstruction from transmission electron microscopy (TEM) images. It was first released in 1999, and new versions...
8.
Rees I, Lee S, Kim H, Tsai F
Biochim Biophys Acta
. 2006 May;
1764(6):1073-9.
PMID: 16725394
In Eukarya, the 26S proteasome is primarily responsible for intracellular protein degradation. To be degraded, proteins must be ubiquitinated. The latter requires a multi-enzyme cascade consisting of an E1, an...