Ian R Booth
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Explore the profile of Ian R Booth including associated specialties, affiliations and a list of published articles.
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57
Citations
1955
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Recent Articles
1.
Neubauer C, Sessions A, Booth I, Bowen B, Kopf S, Newman D, et al.
Rapid Commun Mass Spectrom
. 2018 Sep;
32(24):2129-2140.
PMID: 30252972
Rationale: Microbial growth rate is an important physiological parameter that is challenging to measure in situ, partly because microbes grow slowly in many environments. Recently, it has been demonstrated that...
2.
Pliotas C, Grayer S, Ekkerman S, Chan A, Healy J, Marius P, et al.
Biochemistry
. 2017 Jun;
56(32):4219-4234.
PMID: 28656748
Ligand binding is one of the most fundamental properties of proteins. Ligand functions fall into three basic types: substrates, regulatory molecules, and cofactors essential to protein stability, reactivity, or enzyme-substrate...
3.
Healy J, Rasmussen T, Miller S, Booth I, Conway S
Org Chem Front
. 2016 Apr;
3(4):439-446.
PMID: 27110363
The thiol-ene coupling reaction is emerging as an important conjugation reaction that is suitable for use in a biological setting. Here, we explore the utility of this reaction for the...
4.
Pliotas C, Dahl A, Rasmussen T, Mahendran K, Smith T, Marius P, et al.
Nat Struct Mol Biol
. 2015 Nov;
22(12):991-8.
PMID: 26551077
The ability of proteins to sense membrane tension is pervasive in biology. A higher-resolution structure of the Escherichia coli small-conductance mechanosensitive channel MscS identifies alkyl chains inside pockets formed by...
5.
Altendorf K, Booth I, Gralla J, Greie J, Rosenthal A, Wood J
EcoSal Plus
. 2015 Oct;
3(2).
PMID: 26443764
Escherichia coli and Salmonella encounter osmotic pressure variations in natural environments that include host tissues, food, soil, and water. Osmotic stress causes water to flow into or out of cells,...
6.
Booth I
EcoSal Plus
. 2015 Oct;
1(2).
PMID: 26443506
The metabolic connection between glycerol and methylglyoxal (MG) is principally that DHAP, which is an intermediate in the aerobic breakdown of glycerol, is also the major precursor of MG, being...
7.
Rasmussen T, Rasmussen A, Singh S, Galbiati H, Edwards M, Miller S, et al.
Biochemistry
. 2015 Jul;
54(29):4519-30.
PMID: 26126964
Bacterial mechanosensitive channels gate when the transmembrane turgor rises to levels that compromise the structural integrity of the cell wall. Gating creates a transient large diameter pore that allows hydrated...
8.
Booth I, Miller S, Muller A, Lehtovirta-Morley L
Cell Calcium
. 2015 Jan;
57(3):140-50.
PMID: 25591932
Mechanosensitive channels are ubiquitous and highly studied. However, the evolution of the bacterial channels remains enigmatic. It can be argued that mechanosensitivity might be a feature of all membrane proteins...
9.
Booth I
Curr Opin Microbiol
. 2014 Mar;
18:16-22.
PMID: 24607989
Bacterial mechanosensitive channels sense the changes in lateral tension in the bilayer of the cytoplasmic membrane generated by rapid water flow into the cell. Two major structural families are found...
10.
Healy J, Ekkerman S, Pliotas C, Richard M, Bartlett W, Grayer S, et al.
Biochemistry
. 2014 Mar;
53(12):1982-92.
PMID: 24601535
The potassium efflux system, Kef, protects bacteria against the detrimental effects of electrophilic compounds via acidification of the cytoplasm. Kef is inhibited by glutathione (GSH) but activated by glutathione-S-conjugates (GS-X)...