Ian M Wilson
Overview
Explore the profile of Ian M Wilson including associated specialties, affiliations and a list of published articles.
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13
Citations
389
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Recent Articles
1.
Vucic E, Chari R, Thu K, Wilson I, Cotton A, Kennett J, et al.
Am J Respir Cell Mol Biol
. 2013 Dec;
50(5):912-22.
PMID: 24298892
DNA methylation is an epigenetic modification that is highly disrupted in response to cigarette smoke and involved in a wide spectrum of malignant and nonmalignant diseases, but surprisingly not previously...
2.
Lockwood W, Wilson I, Coe B, Chari R, Pikor L, Thu K, et al.
PLoS One
. 2012 May;
7(5):e37775.
PMID: 22629454
For therapeutic purposes, non-small cell lung cancer (NSCLC) has traditionally been regarded as a single disease. However, recent evidence suggest that the two major subtypes of NSCLC, adenocarcinoma (AC) and...
3.
Thu K, Pikor L, Chari R, Wilson I, MacAulay C, English J, et al.
J Thorac Oncol
. 2011 Jul;
6(9):1521-9.
PMID: 21795997
Introduction: Inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (IKBKB) (IKK-β/IKK-2), which activates NF-κB, is a substrate of the KEAP1-CUL3-RBX1 E3-ubiquitin ligase complex, implicating this complex in...
4.
Cotton A, Lam L, Affleck J, Wilson I, Penaherrera M, McFadden D, et al.
Hum Genet
. 2011 May;
130(2):187-201.
PMID: 21597963
X-chromosome inactivation (XCI) results in the differential marking of the active and inactive X with epigenetic modifications including DNA methylation. Consistent with the previous studies showing that CpG island-containing promoters...
5.
Lonergan K, Chari R, Coe B, Wilson I, Tsao M, Ng R, et al.
PLoS One
. 2010 Feb;
5(2):e9162.
PMID: 20161782
Background: Non-small cell lung cancer (NSCLC) presents as a progressive disease spanning precancerous, preinvasive, locally invasive, and metastatic lesions. Identification of biological pathways reflective of these progressive stages, and aberrantly...
6.
Chari R, Thu K, Wilson I, Lockwood W, Lonergan K, Coe B, et al.
Cancer Metastasis Rev
. 2010 Jan;
29(1):73-93.
PMID: 20108112
Advances in high-throughput, genome-wide profiling technologies have allowed for an unprecedented view of the cancer genome landscape. Specifically, high-density microarrays and sequencing-based strategies have been widely utilized to identify genetic...
7.
Mehanna P, Leinkram D, Wilson I
N Z Med J
. 2009 Oct;
122(1302):100-2.
PMID: 19834528
No abstract available.
8.
Vucic E, Wilson I, Campbell J, Lam W
Methods Mol Biol
. 2009 Jun;
556:141-53.
PMID: 19488876
Alteration in epigenetic regulation of gene expression is a common event in human cancer and developmental disease. CpG island hypermethylation and consequent gene silencing is observed for many genes involved...
9.
Thu K, Vucic E, Kennett J, Heryet C, Brown C, Lam W, et al.
J Vis Exp
. 2009 Feb;
(23).
PMID: 19241501
The identification of DNA methylation patterns is a common procedure in the study of epigenetics, as methylation is known to have significant effects on gene expression, and is involved with...
10.
Chari R, Coe B, Wedseltoft C, Benetti M, Wilson I, Vucic E, et al.
BMC Bioinformatics
. 2008 Oct;
9:422.
PMID: 18840289
Background: High throughput microarray technologies have afforded the investigation of genomes, epigenomes, and transcriptomes at unprecedented resolution. However, software packages to handle, analyze, and visualize data from these multiple 'omics...