Ian Hutchinson
Overview
Explore the profile of Ian Hutchinson including associated specialties, affiliations and a list of published articles.
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Articles
48
Citations
433
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0
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Recent Articles
1.
Allen R, Boden L, Hutchinson I, Stirling J, Porphyre T
Res Vet Sci
. 2024 Sep;
180:105413.
PMID: 39270505
Background: Livestock markets are critical intermediaries in the movement of cattle and sheep between herds and to abattoirs. Disease prevention strategies promoting Cleansing & Disinfection (C&D) of vehicles moving animals...
2.
Lindborg C, Smith R, Reihl A, Bacevich B, Cote M, ODonnell E, et al.
J Clin Med
. 2024 Apr;
13(5).
PMID: 38592250
: The management of acromioclavicular joint injuries requires a thorough understanding of the anatomy and biomechanics of the joint, as well as knowledge of the pertinent physical exam findings and...
3.
Kinneer K, Wortmann P, Cooper Z, Dickinson N, Masterson L, Cailleau T, et al.
Clin Cancer Res
. 2022 Nov;
29(6):1086-1101.
PMID: 36355054
Purpose: We evaluated the activity of AZD8205, a B7-H4-directed antibody-drug conjugate (ADC) bearing a novel topoisomerase I inhibitor (TOP1i) payload, alone and in combination with the PARP1-selective inhibitor AZD5305, in...
4.
Gregson S, Pugh K, Patel N, Afif-Rider S, Vijayakrishnan B, Santos K, et al.
Mol Cancer Ther
. 2022 Jul;
21(9):1439-1448.
PMID: 35793464
Antibody-drug conjugate (ADC) research has typically focused on the release of highly potent cytotoxic agents to achieve antitumor efficacy. However, recently approved ADCs trastuzumab deruxtecan and sacituzumab govitecan release lower-potency...
5.
Vig K, Amarante M, Hutchinson I, Lawrence J
N Am Spine Soc J
. 2022 Feb;
6:100067.
PMID: 35141632
Background: Spinal epidural abscess (SEA) in children is a rare condition with dangerous sequelae, and with only 22 other cases reported in the literature, treatment algorithms are poorly understood. Quick...
6.
Posner A, Hutchinson I, Zimmerman J
Arthrosc Tech
. 2021 Jul;
10(6):e1447-e1453.
PMID: 34258189
Transverse patella fractures with loss of knee extensor mechanism function are a common orthopaedic injury requiring operative fixation. Current accepted surgical options for noncomminuted transverse fractures include open reduction with...
7.
Titan A, Schar M, Hutchinson I, Demange M, Chen T, Rodeo S
Arthroscopy
. 2019 Dec;
36(5):1431-1440.
PMID: 31862290
Purpose: To determine whether (1) human leukocyte-platelet-rich plasma (L-PRP) or (2) leukocyte-platelet-rich fibrin (L-PRF) delivered on a hyaluronic acid (HA) scaffold at a bovine chondral defect, a simulated cartilage tear...
8.
Porphyre T, Correia-Gomes C, Chase-Topping M, Gamado K, Auty H, Hutchinson I, et al.
Sci Rep
. 2017 Feb;
7:42992.
PMID: 28225040
Classical swine fever (CSF) is a notifiable, highly contagious viral disease of swine which results in severe welfare and economic consequences in affected countries. To improve preparedness, it is critical...
9.
Straightforward Glycoengineering Approach to Site-Specific Antibody-Pyrrolobenzodiazepine Conjugates
Thompson P, Ezeadi E, Hutchinson I, Fleming R, Bezabeh B, Lin J, et al.
ACS Med Chem Lett
. 2016 Nov;
7(11):1005-1008.
PMID: 27882199
Antibody-drug conjugates (ADCs) have become a powerful platform to deliver cytotoxic agents selectively to cancer cells. ADCs have traditionally been prepared by stochastic conjugation of a cytotoxic drug using an...
10.
Malherbe C, Ingley R, Hutchinson I, Edwards H, Carr A, Harris L, et al.
Astrobiology
. 2015 Jun;
15(6):442-52.
PMID: 26060982
Desert varnishes are thin, dark mineral coatings found on some rocks in arid or semi-arid environments on Earth. Microorganisms may play an active role in their formation, which takes many...