Ian Duguid
Overview
Explore the profile of Ian Duguid including associated specialties, affiliations and a list of published articles.
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Articles
19
Citations
635
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0
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Recent Articles
1.
Sanchez Rivera M, Duguid I
Neuron
. 2025 Feb;
113(4):503-505.
PMID: 39978313
In this issue of Neuron, Park et al. show that striatal activity is necessary for the specification of movement kinematics using a novel reach-to-pull task for mice. Through simultaneous cortical...
2.
OKeeffe M, Booker S, Walsh D, Li M, Henley C, Simoes de Oliveira L, et al.
Nat Neurosci
. 2025 Jan;
28(2):268-279.
PMID: 39762658
Brain-resident macrophages, microglia, have been proposed to have an active role in synaptic refinement and maturation, influencing plasticity and circuit-level connectivity. Here we show that several neurodevelopmental processes previously attributed...
3.
Stuart S, Palacios-Filardo J, Domanski A, Udakis M, Duguid I, Jones M, et al.
Sci Rep
. 2024 Jun;
14(1):14315.
PMID: 38906952
Head-fixation of mice enables high-resolution monitoring of neuronal activity coupled with precise control of environmental stimuli. Virtual reality can be used to emulate the visual experience of movement during head...
4.
Dura-Bernal S, Neymotin S, Suter B, Dacre J, Moreira J, Urdapilleta E, et al.
Cell Rep
. 2023 Jun;
42(6):112574.
PMID: 37300831
Understanding cortical function requires studying multiple scales: molecular, cellular, circuit, and behavioral. We develop a multiscale, biophysically detailed model of mouse primary motor cortex (M1) with over 10,000 neurons and...
5.
Dacre J, Sanchez Rivera M, Schiemann J, Currie S, Ammer J, Duguid I
J Neurosci Methods
. 2023 Mar;
390:109827.
PMID: 36871604
Background: In vivo patch-clamp recording techniques provide access to the sub- and suprathreshold membrane potential dynamics of individual neurons during behavior. However, maintaining recording stability throughout behavior is a significant...
6.
Eleftheriou C, Clarke T, Poon V, Zechner M, Duguid I
J Neurosci Methods
. 2023 Jan;
386:109779.
PMID: 36621552
Background: Touchscreen-based behavioral assays provide a robust method for assessing cognitive behavior in rodents, offering great flexibility and translational potential. The development of touchscreen assays presents a significant programming and...
7.
Currie S, Ammer J, Premchand B, Dacre J, Wu Y, Eleftheriou C, et al.
Cell Rep
. 2022 May;
39(6):110801.
PMID: 35545038
Motor cortex generates descending output necessary for executing a wide range of limb movements. Although movement-related activity has been described throughout motor cortex, the spatiotemporal organization of movement-specific signaling in...
8.
Dacre J, Colligan M, Clarke T, Ammer J, Schiemann J, Chamosa-Pino V, et al.
Neuron
. 2021 Jun;
109(14):2326-2338.e8.
PMID: 34146469
Executing learned motor behaviors often requires the transformation of sensory cues into patterns of motor commands that generate appropriately timed actions. The cerebellum and thalamus are two key areas involved...
9.
Garden D, Oostland M, Jelitai M, Rinaldi A, Duguid I, Nolan M
Cell Rep
. 2018 Feb;
22(7):1722-1733.
PMID: 29444426
Cerebellar climbing-fiber-mediated complex spikes originate from neurons in the inferior olive (IO), are critical for motor coordination, and are central to theories of cerebellar learning. Hyperpolarization-activated cyclic-nucleotide-gated (HCN) channels expressed...
10.
Brenowitz S, Duguid I, Kammermeier P
Cold Spring Harb Protoc
. 2017 Jul;
2017(7):pdb.top092288.
PMID: 28679719
From patch-clamp techniques to recombinant DNA technologies, three-dimensional protein modeling, and optogenetics, diverse and sophisticated methods have been used to study ion channels and how they determine the electrical properties...