I Wessler
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Explore the profile of I Wessler including associated specialties, affiliations and a list of published articles.
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89
Citations
1465
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Recent Articles
1.
Bateman E, Rennard S, Barnes P, Dicpinigaitis P, Gosens R, Gross N, et al.
Pulm Pharmacol Ther
. 2009 Jul;
22(6):533-42.
PMID: 19635581
Tiotropium is commonly used in the treatment of chronic obstructive pulmonary disease. Although largely considered to be a long-acting bronchodilator, its demonstrated efficacy in reducing the frequency of exacerbations and...
2.
Wessler I, Kirkpatrick C
Br J Pharmacol
. 2008 May;
154(8):1558-71.
PMID: 18500366
Animal life is controlled by neurons and in this setting cholinergic neurons play an important role. Cholinergic neurons release ACh, which via nicotinic and muscarinic receptors (n- and mAChRs) mediate...
3.
Kurzen H, Wessler I, Kirkpatrick C, Kawashima K, Grando S
Horm Metab Res
. 2007 Feb;
39(2):125-35.
PMID: 17326008
In human skin both resident and transiently residing cells are part of the extra- or non-neuronal cholinergic system, creating a highly complex and interconnected cosmos in which acetylcholine (ACh) and...
4.
Steffl M, Schweiger M, Wessler I, Kunz L, Mayerhofer A, Amselgruber W
Anat Embryol (Berl)
. 2006 Oct;
211(6):685-90.
PMID: 17024297
Certain female reproductive tissues are known to express the non-neuronal cholinergic system. Using different experimental approaches, we tested the hypothesis that acetylcholine (ACh) in the porcine oviduct may also be...
5.
Helisch A, Schirrmacher E, Thews O, Schirrmacher R, Buchholz H, Dillenburg W, et al.
Eur J Nucl Med Mol Imaging
. 2005 Sep;
32(11):1324-8.
PMID: 16133376
Purpose: The new beta2 radioligand (R,R)(S,S) 5-(2-(2-[4-(2-[18F]fluoroethoxy)phenyl]-1-methylethylamino)-1-hydroxyethyl)-benzene-1,3-diol ([18F]FE-fenoterol; [18F]FEFE), a fluoroethylated derivative of racemic fenoterol, was evaluated in vivo and ex vivo using a guinea pig model. Methods: Dynamic PET...
6.
Wessler I, Burger R, Doppelfeld E
Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz
. 2005 Feb;
48(2):155-67.
PMID: 15726456
Since 12(th) of August 2004 the EU Directive 2001/20/EG has been implemented into the national law. The 12th AMG amendment of 30 July 2004 and the good clinical practice decree...
7.
Wessler I, Roth E, Deutsch C, Brockerhoff P, Bittinger F, Kirkpatrick C, et al.
Br J Pharmacol
. 2001 Oct;
134(5):951-6.
PMID: 11682442
1. The release of acetylcholine was investigated in the human placenta villus, a useful model for the characterization of the non-neuronal cholinergic system. 2. Quinine, an inhibitor of organic cation...
8.
Wessler I, Roth E, Schwarze S, Weikel W, Bittinger F, Kirkpatrick C, et al.
Naunyn Schmiedebergs Arch Pharmacol
. 2001 Aug;
364(3):205-12.
PMID: 11521162
The synthesis and release of non-neuronal acetylcholine, a widely expressed signaling molecule, were investigated in the human placenta. This tissue is free of cholinergic neurons, i.e. a contamination of neuronal...
9.
Kirkpatrick C, Bittinger F, Unger R, Kriegsmann J, Kilbinger H, Wessler I
Jpn J Pharmacol
. 2001 Mar;
85(1):24-8.
PMID: 11243570
An increasing body of knowledge indicates that the cholinergic system is not confined to the nervous system, but is practically ubiquitous. The present paper will address the question of the...
10.
Wessler I, Kilbinger H, Bittinger F, Kirkpatrick C
Jpn J Pharmacol
. 2001 Mar;
85(1):2-10.
PMID: 11243568
Acetylcholine, one of the most exemplary neurotransmitters, has been detected in bacteria, algae, protozoa, tubellariae and primitive plants, suggesting an extremely early appearance in the evolutionary process and a wide...