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I Van Seuningen

Explore the profile of I Van Seuningen including associated specialties, affiliations and a list of published articles. Areas
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Articles 25
Citations 718
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Recent Articles
1.
Lahdaoui F, Delpu Y, Vincent A, Renaud F, Messager M, Duchene B, et al.
Oncogene . 2014 Mar; 34(6):780-8. PMID: 24608432
Pancreatic ductal adenocarcinoma (PDAC) is among the most lethal cancers in the world with one of the worst outcome. The oncogenic mucin MUC4 has been identified as an actor of...
2.
Skrypek N, Duchene B, Hebbar M, Leteurtre E, Van Seuningen I, Jonckheere N
Oncogene . 2012 May; 32(13):1714-23. PMID: 22580602
The fluorinated analog of deoxycytidine, Gemcitabine (Gemzar), is the main chemotherapeutic drug in pancreatic cancer, but survival remains weak mainly because of the high resistance of tumors to the drug....
3.
Merlin J, Stechly L, De Beauce S, Monte D, Leteurtre E, Van Seuningen I, et al.
Oncogene . 2011 Jan; 30(22):2514-25. PMID: 21258405
MUC1 is a transmembrane glycoprotein which is typically expressed at the apical membrane of normal epithelial cells. In cancer cells, the over-expression of MUC1 and its aberrant localization around the...
4.
Piessen G, Wacrenier A, Briez N, Triboulet J, Van Seuningen I, Mariette C
J Clin Pathol . 2009 Dec; 62(12):1144-6. PMID: 19946103
Aims: To study the expression of MUC1 and MUC4 mucins in Barrett-associated oesophageal adenocarcinoma and coexisting lesions of the carcinogenic sequence (normal mucosa, metaplasia, dysplasia) if present, and to investigate...
5.
Jonckheere N, Fauquette V, Stechly L, Saint-Laurent N, Aubert S, Susini C, et al.
Br J Cancer . 2009 Aug; 101(4):637-44. PMID: 19672266
Background: Activator protein-2alpha (AP-2alpha) is a transcription factor that belongs to the family of AP-2 proteins that have essential roles in tumorigenesis. Indeed, AP-2alpha is considered as a tumour-suppressor gene...
6.
Barros R, Pereira B, Duluc I, Azevedo M, Mendes N, Camilo V, et al.
J Pathol . 2008 May; 215(4):411-20. PMID: 18498120
Helicobacter pylori infection induces intestinal metaplasia of the stomach, a preneoplastic lesion associated with an increased risk for gastric cancer development. Intestinal metaplasia is induced by the intestine-specific transcription factor...
7.
Vincent A, Perrais M, Desseyn J, Aubert J, Pigny P, Van Seuningen I
Oncogene . 2007 May; 26(45):6566-76. PMID: 17471237
The human genes MUC2, MUC5AC, MUC5B and MUC6 are clustered on chromosome 11 and encode large secreted gel-forming mucins. The frequent occurrence of their silencing in cancers and the GC-rich...
8.
Singh A, Chauhan S, Andrianifahanana M, Moniaux N, Meza J, Copin M, et al.
Oncogene . 2006 Jun; 26(1):30-41. PMID: 16799633
MUC4 mucin is a high molecular weight transmembrane glycoprotein that plays important roles in tumour biology. It is aberrantly expressed in pancreatic adenocarcinoma, while not being detectable in the normal...
9.
Mariette C, Piessen G, Balon J, Van Seuningen I, Triboulet J
Eur J Surg Oncol . 2004 Sep; 30(8):869-76. PMID: 15336734
Aim: To document the results of surgery alone in patients with localised oesophageal carcinoma. Methods: Between January 1982 and 2002, 179 consecutive patients who underwent curative oesophagectomy for stage 0,...
10.
Mariette C, Balon J, Maunoury V, Taillier G, Van Seuningen I, Triboulet J
Br J Surg . 2003 Nov; 90(11):1367-72. PMID: 14598416
Background: : Endoscopic ultrasonography (EUS) is considered to be the best locoregional staging technique for cancer of the oesophagus. This study evaluated the relationship between preoperative EUS findings, completeness of...